Uveitis

This study tests a new drug, GenSci048, in people with active non-infectious uveitis, an inflammatory eye disease. The trial will compare two doses of GenSci048 against a placebo to see if it can control the disease and reduce treatment failure. About 111 adults with active uveit…

This study tests the drug adalimumab (Tebiovio®) in 30 adults with non-infectious uveitis, an inflammatory eye disease. The goal is to see if the drug can control inflammation and prevent treatment failure. Participants will receive injections and be monitored for up to 24 weeks.…

This early-stage trial tests an oral drug called DF-003 in 12 people with ROSAH syndrome, a rare genetic condition causing eye inflammation, enlarged spleen, and headaches. The main goal is to check safety and how the body processes the drug, while also watching for improvements …

This study tests an oral medication called FXS5626 in 40 adults with active non-infectious uveitis, a condition causing inflammation inside the eye. The goal is to see if the drug can control the disease better than a placebo, reducing the need for other treatments. Participants …

Uveitis is an inflammation inside the eye that can cause permanent vision loss in children, often without symptoms. This study compares a high-resolution, non-contact eye scan called AS-OCT with the standard slit-lamp eye exam in 300 children aged 2 to 16 who attend a pediatric u…

This study tests a new diagnostic method called metagenomic sequencing to find hidden infections in people with eye inflammation (uveitis). Standard tests often miss the cause. Researchers will analyze fluid from the eye to detect bacteria, viruses, fungi, or parasites. The goal …

This study is observing 300 children under 18 with uveitis, an eye inflammation condition. Researchers want to learn how common different types of uveitis are and what treatments children receive. Participants have one visit with their doctor, and some will have their medical rec…

This study is tracking 290 children with non-infectious chronic uveitis, a rare eye inflammation that can cause vision loss. Researchers will collect data on symptoms, lab results, and complications over several years. The goal is to better understand the disease and identify ris…

This study is testing whether a special eye scan (OCT) can accurately measure inflammation inside the eye for people with uveitis. Researchers will scan the eyes of 1500 patients and compare the results to standard exams. The goal is to find a faster, painless way to track diseas…

This study aims to uncover genetic mutations or variations linked to uveitis, an inflammatory eye disease. Researchers will collect blood samples from 1,500 patients with uveitis (including infectious types) and analyze their DNA. The goal is to better understand what causes the …