Acute posterior multifocal placoid pigment epitheliopathy
MONDO:0043089Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an acquired, inflammatory eye condition affecting the retina, retinal pigment epithelium (pigmented layer of the retina), and choroid. It usually affects both eyes and is characterized by multiple, yellow-white lesions in the back of the eye. The condition can significantly impair visual acuity if the macula is involved. APMPPE typically resolves on its own in weeks to months. While the cause is unknown, about a third of cases appear to develop after a flu-like illness. Non-ocular symptoms are uncommon, but cerebral vasculitis can be present and may cause permanent and/or severe neurological complications.
Also known as: Epitheliopathy, Acute Posterior Multifocal Placoid Pigment, acute posterior multifocal placoid pigment epitheliopathy, AMPPE, APMPPE, acute multifocal placoid pigment epitheliopathy, acute placoid pigment epitheliopathy, amppe - acute multifocal placoid pigment epitheliopathy, apmppe
4 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
New study aims to uncover uveitis patterns in kids
Knowledge-focused Recruiting nowThis study is observing 300 children under 18 with uveitis, an eye inflammation condition. Researchers want to learn how common different types of uveitis are and what treatments children receive. Participants have one visit with their doctor, and some will have their medical rec…
Sponsor: Jaeb Center for Health Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
-
Vasculitis patients wanted for major 5-Year observation study
Knowledge-focused Recruiting nowThis study is following 670 adults with vasculitis, a rare blood vessel disease, for up to 5 years. Researchers will collect medical data and blood samples to see how the disease starts, how it is treated, and what long-term problems may arise. No new treatments are being tested—…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:31 UTC