Transplant rejection
MONDO:1010185A disease related to transplantation that occurs when transplant tissue is rejected by the recipient's immune system, which destroys the transplanted tissue.
Also known as: host versus graft disease, host vs graft disease
147 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Can a simple drug make donated kidneys start working faster?
Disease control TerminatedThis study tested whether the drug heme arginate can help transplanted kidneys work right away, instead of being slow to start. It included 47 adults receiving a kidney from a deceased donor. Participants got either the drug or a salt water solution at transplant and 24 hours lat…
Phase: PHASE3 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Kidney transplant study tests Once-Daily pill to replace Twice-Daily dosing
Disease control TerminatedThis study tested whether a once-daily extended-release form of tacrolimus (Envarsus XR) combined with azathioprine could work as well as the standard twice-daily tacrolimus plus mycophenolate in preventing kidney transplant rejection. The trial planned to enroll 20 adults receiv…
Phase: PHASE4 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Breathing in a special gas reveals hidden lung damage in transplant patients
Knowledge-focused TerminatedThis study used a special MRI technique with a harmless gas called hyperpolarized xenon-129 to take detailed pictures of lung function in people who had a lung transplant. The goal was to see if this scan could detect early signs of chronic lung allograft dysfunction (CLAD), a co…
Sponsor: Xemed LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Xenon gas MRI could spot lung transplant rejection early
Knowledge-focused TerminatedThis study tested a new type of MRI that uses inhaled xenon gas to create detailed images of the lungs. The goal was to see if it could detect early signs of chronic rejection in lung transplant recipients. Only 6 adults who had double lung transplants took part, and the study wa…
Phase: PHASE2 • Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:27 UTC