Can a single drug make donated kidneys start working faster?

NCT ID NCT03646344

First seen Nov 17, 2025 · Last updated May 07, 2026 · Updated 23 times

Summary

This study tested whether the drug heme arginate could help transplanted kidneys work immediately, especially when the kidney comes from an older donor. About 600 kidney transplant patients were planned, but the study was stopped early with only 47 participants. Patients received either the drug or a salt water solution at the time of transplant and 24 hours later, and kidney function was monitored for the first week.

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Contacts and locations

Locations

  • Edinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh

    Edinburgh, EH16 4UX, United Kingdom

  • NHS Lothian - Royal Infirmary of Edinburgh

    Edinburgh, Lothian, EH16 4SA, United Kingdom

Conditions

Explore the condition pages connected to this study.