Can a simple drug make donated kidneys start working faster?

NCT ID NCT03646344

Terminated Disease control Sponsor: University of Edinburgh Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether the drug heme arginate can help transplanted kidneys work right away, instead of being slow to start. It included 47 adults receiving a kidney from a deceased donor. Participants got either the drug or a salt water solution at transplant and 24 hours later. The goal was to see if the drug reduces the need for dialysis and improves early kidney function.

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Conditions

The condition(s) this trial relates to.

acute transplant rejection Delayed Graft Function end stage renal failure transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RENAL TRANSPLANT FAILURE RENAL TRANSPLANT REJECTION

Contacts and locations

Locations

Edinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh

Edinburgh, EH16 4UX, United Kingdom
NHS Lothian - Royal Infirmary of Edinburgh

Edinburgh, Lothian, EH16 4SA, United Kingdom

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