Xenon gas MRI could spot lung transplant rejection early
NCT ID NCT05550662
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested a new type of MRI that uses inhaled xenon gas to create detailed images of the lungs. The goal was to see if it could detect early signs of chronic rejection in lung transplant recipients. Only 6 adults who had double lung transplants took part, and the study was stopped early. The approach is still experimental.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hyperpolarized xenon gas
What this could lead to
If successful, this imaging method could help doctors spot early signs of lung transplant rejection without invasive biopsies.
What could go wrong
This was a very small, early feasibility study with only 6 participants and was terminated early, so results are limited and may not apply broadly.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital for Sick Chilldren
Toronto, Ontario, M5G 1X8, Canada
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The Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada