Special MRI could spot lung rejection early, saving transplants
NCT ID NCT07046910
First seen Mar 27, 2026 · Last updated Jun 22, 2026 · Updated 15 times
Summary
This study tests whether a special MRI using inhaled xenon gas can detect early signs of rejection in lung transplant patients. Researchers will compare MRI results with lung function tests and cell analysis from fluid samples. The goal is to find a non-invasive way to catch rejection sooner, which could help prevent long-term graft failure.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22908, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hyperpolarized Xenon-129 gas
What this could lead to
If successful, this MRI method could allow doctors to detect lung transplant rejection earlier and more accurately, potentially improving patient outcomes.
What could go wrong
This is a small, early-phase study (60 participants) focused on diagnosis, not treatment. The MRI technique may not prove reliable enough for routine use.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.