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Strabismus
MONDO:0003432Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected.
Also known as: squint, strabismus
38 clinical trials for this condition and its sub-types.
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Broader categories
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New study tests best glasses for kids with wandering eyes and nearsightedness
Disease control Not yet recruitingThis study compares two types of special glasses (DIMS and DOT) to control nearsightedness in children aged 6 to 12 who also have intermittent exotropia (a type of eye misalignment). Researchers want to see which lens works better and whether the glasses affect eye coordination. …
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Eye exercises may offer Non-Surgical hope for wandering eyes
Disease control Not yet recruitingThis study tests whether 12 sessions of visual therapy (eye exercises) can improve eye alignment and quality of life in people aged 8 to 50 with intermittent horizontal strabismus (eyes that sometimes wander). Participants are randomly assigned to either the therapy group or a no…
Phase: NA • Sponsor: Universitat Politècnica de Catalunya • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Botox injections could replace surgery for kids with crossed eyes
Disease control Not yet recruitingThis study compares Botox injections to standard surgery for treating childhood esotropia (crossed eyes) in 244 children. The goal is to see if Botox, a less invasive option, works as well as surgery to straighten the eyes. If successful, it could reduce risks from surgery and an…
Phase: PHASE3 • Sponsor: Jaeb Center for Health Research • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Botox shots in the eye may replace surgery for strabismus
Disease control Not yet recruitingThis study tests whether injecting Botox into the eye muscles can correct strabismus (misaligned eyes) without surgery. 127 children and adults with small-to-moderate eye turns will receive Botox injections, and their eye alignment will be tracked for a year. The goal is to see i…
Phase: NA • Sponsor: Foundation University Islamabad • Aim: Disease control
Last updated Jun 26, 2026 17:52 UTC
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Your phone camera could soon spot eye disorders
Diagnosis Not yet recruitingThis study will check if an AI system can accurately measure eye movements from smartphone videos. About 1,000 adults with suspected eye movement issues will record a short video while following a moving target. The AI's measurements will be compared to expert ratings to see if i…
Sponsor: THYROSCOPE INC. • Aim: Diagnosis
Last updated Jun 27, 2026 13:01 UTC
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3D movies could be a fun new treatment for lazy eye in children
Symptom relief Not yet recruitingThis study tests whether watching 3D movies, combined with standard patching therapy, improves depth perception and vision in children aged 4 to 14 with amblyopia (lazy eye). Half the children will receive patching alone, while the other half will also attend weekly 3D movie sess…
Phase: NA • Sponsor: Universitat Politècnica de Catalunya • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New study aims to improve comfort during eye muscle surgery
Symptom relief Not yet recruitingThis study compares two anesthesia methods for strabismus (eye muscle) surgery in adults: general anesthesia (being fully asleep) versus a combination of sedation with a local numbing injection around the eye. Researchers will measure patient and surgeon satisfaction with each ap…
Phase: NA • Sponsor: Sohag University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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3D movies may boost depth perception in kids with lazy eye
Symptom relief Not yet recruitingThis study tests whether watching 3D movies can improve depth perception and vision in children aged 4 to 12 who still have some vision loss from lazy eye (amblyopia) despite prior treatment. Forty children will be randomly assigned to watch three movies in either 3D or 2D, then …
Phase: NA • Sponsor: Universitat Politècnica de Catalunya • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Morning or evening patching for lazy eye? study seeks best timing
Symptom relief Not yet recruitingThis study tests whether patching the stronger eye in the morning (8-10 AM) or evening (5-7 PM) works better for improving vision in children with lazy eye (amblyopia). About 100 children aged 4-8 will wear an eye patch for 2-6 hours daily over 6 months. The goal is to see if tim…
Phase: NA • Sponsor: Yarmouk University • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Eye twitch may signal early MS, new study hopes to find out
Knowledge-focused Not yet recruitingThis study examines patients who have internuclear ophthalmoplegia, a condition that causes trouble moving the eyes sideways, to see how many later develop multiple sclerosis (MS). Researchers will review medical records of 200 patients to identify factors that predict MS convers…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Second Time's the charm? new study investigates repeat strabismus surgery
Knowledge-focused Not yet recruitingThis study follows 62 people who need a second surgery for crossed or wandering eyes (strabismus). Researchers want to find out what factors increase the risk of needing repeat surgery and how successful the second operation is. Participants get a personalized surgical plan and a…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Eye muscle width may predict surgery success for crossed eyes
Knowledge-focused Not yet recruitingThis study will measure the width of the medial rectus tendon in 28 people having surgery for crossed eyes (esotropia). The goal is to see if tendon width is linked to how much the eye position changes after surgery. If a link is found, it could help surgeons plan more precise op…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:38 UTC