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This study tested whether analyzing a patient's DNA and RNA could help doctors pick the right drug for inflammatory diseases that don't fit standard categories. 32 adults with at least two affected organs (including skin) received one of six targeted therapies based on their mole…

This study followed 77 adults who received spinal implants (PASS LP, PASS DEGEN, or PASS TULIP PRIME) to treat degenerative spine conditions like disc degeneration or spinal deformity. The main goal was to see if the bones fused properly after 24 months. Researchers also tracked …

This study looked at the long-term safety and effectiveness of the Birmingham Hip Resurfacing System, a metal hip implant, in 329 adults with arthritis. The main goal was to see how many patients needed a revision (replacement or removal) within 10 years. The study also measured …

This study looked at how well a specific knee replacement (balanSys UNI) works over time. 116 people with knee arthritis got the implant and were followed for at least 2 years. Doctors measured knee function using the Knee Society Score and checked X-rays for any problems.

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…

This study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…

This study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…

This early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …

This early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…

This pilot study looked at whether passive static stretching can increase hip flexibility in three groups: people who had hip replacement, those with long-term hip pain, and healthy volunteers. Twelve participants followed a 4-week stretching program three times a week under supe…

This study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…

This study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…

This study tested whether a probiotic called Bifidobacterium breve PRL2020 could reduce stomach issues like diarrhea in 121 children aged 3-12 who were taking amoxicillin antibiotics. The children took the probiotic alongside their antibiotic treatment. The goal was to see if it …

This study compared robotic-assisted total knee replacement to the conventional technique in 95 patients with knee arthritis. The goal was to see if robotic surgery leads to better knee function, less pain, and higher satisfaction two years after the operation. Researchers also c…

This pilot study tested whether using ultrasound to guide pharmacopuncture (herbal injections) is safe and effective for neck and back pain. Fifty adults with spinal disorders received the treatment, and researchers tracked side effects, pain levels, disability, and quality of li…

This completed study looked at how the social networks of caregivers affect their stress and health when caring for someone with an inherited disease. Researchers surveyed over 680 participants, including family members and formal caregivers, to understand caregiving burden and s…

This study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…

This study looked at 335 adults hospitalized with bacterial infections to see if taking NSAIDs (like ibuprofen) before admission made their infections more severe. Researchers compared those with complicated infections (abscesses, needing surgery) to those with simpler infections…

This study gathered information from 193 adults who had surgery or orthopedic treatment for spine problems. Researchers collected clinical, functional, and social data to create a detailed database. The goal was to better understand patient outcomes and standardize how data is co…

This study looked at 120 adults with neck or lower back spine issues to compare two types of scans: contrast-enhanced MRI and FDG-PET/CT. Researchers checked how clear the images were and whether the scans caused any short-term changes in kidney function or blood counts. The goal…

This completed study looked at how the skeleton is aligned with gravity in adults with postural problems. Researchers used a low-dose X-ray device called EOS to create 3D images of the spine and pelvis. The goal was to better understand the body's geometry in people with balance …

This study looked at DNA methylation patterns in stored samples from 90 patients with rare skeletal disorders, sarcomas, or inflammatory arthritis. The goal was to better understand these patterns and explore their potential for diagnosis and treatment. The research aimed to impr…

This study tested a new lightweight device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Fourteen adults having spine surgery used the device to guide screw placement. The goal was to see if the device reduces screw misplacement and is safe…

This study aimed to find the best dose of the antibiotic ceftazidime for critically ill children with severe burns. Researchers took blood samples from 3 children to measure how the drug moves through the body. The goal was to learn how to personalize dosing to improve treatment …

This study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…

This early-phase study tested a single dose of the antibiotic omadacycline (Nuzyra) in 23 children aged 8 to 17 who were hospitalized with bacterial infections. Researchers measured how the drug moved through the body and checked for side effects. The goal was to gather safety an…

This study tested a new imaging technique using a radioactive tracer called 11C-trimethoprim to see how it spreads in the bodies of 16 adults with suspected bacterial infections. Participants had PET/CT scans to track the tracer over time. The goal was to learn how the tracer beh…

This study collected information from over 8,000 people who had spine surgery for conditions like degeneration, deformity, or trauma. Researchers gathered X-ray and health data to learn which treatments work best for different patients. The goal was to build a database to answer …

This study collected stool samples from 14 patients with bone or joint infections who were receiving long-term antibiotics injected under the skin. The goal was to build a biological sample bank for future research on how gut bacteria develop resistance to antibiotics. No treatme…

This completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …

This study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …

This completed pilot study tested whether training doctors to ask personalized questions (individuation) could improve care for Black and lower-income patients with rheumatic diseases like lupus and arthritis. Over 200 patients and their rheumatologists took part. The goal was to…

This study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …

This study reviewed the records of 978 adults who had spinal fusion surgery to see how often routine follow-up X-rays led to additional tests or changes in treatment. The goal is to find out whether these X-rays are truly helpful or if they can be skipped. The results could help …

This study tested special wearable pumps (elastomeric pumps) to give antibiotics through a drip to hospital patients. Nine adults with bacterial infections took part to see if the pumps are safe, easy to use, and could save time and money compared to traditional methods. The goal…

This study looked at two different designs of knee replacement implants in 60 people with arthritis. The goal was to see how much each implant moved inside the bone over two years using a special X-ray technique called RSA. The findings could help surgeons pick the better implant…