Staphylococcus aureus infection

This early-stage study tested a new vaccine called LTB-SA7 designed to protect against infections caused by Staphylococcus aureus bacteria. 129 healthy adults received either the vaccine or a placebo to check for safety and to see if the vaccine triggers an immune response. The s…

This pilot study compares a new decolonization regimen using polyhexanide (nasal gel and body foam) to the standard mupirocin and chlorhexidine treatment for reducing Staphylococcus aureus bacteria before elective spine surgery. The trial includes 24 adults who carry Staph bacter…

This study tested whether a combination of topical antibiotics and antiseptic washes could reduce staph bacteria on the skin of Native American adults living on or near tribal lands. Participants were at high risk for staph infections due to diabetes, obesity, or recent infection…

This completed trial tested a centralized care model for patients with serious staph bloodstream infections. Over 2,500 adults in Alberta hospitals received automated alerts and expert recommendations to ensure they got the right tests, antibiotics, and specialist care. The goal …

This study tested a new medicine called AP-SA02, given through a vein, along with standard antibiotics for adults with a Staph blood infection. The main goal was to check if the combination is safe and tolerable. Researchers also looked at whether it helped clear the infection fa…

This study tested a lab-made antibody called 514G3 in 52 hospitalized adults with Staphylococcus aureus bloodstream infections. Participants received either a single dose of the antibody plus standard antibiotics or a placebo plus antibiotics. The main goals were to check safety …

This study tested whether combining personal hygiene (using medicated washes and ointments) with household cleaning can prevent MRSA skin infections. Over 800 people from households with a recent MRSA infection took part. The goal was to see if this combined approach reduces the …

This study looked at a new lab test called Antibiofilmogramme for people with diabetic foot infections caused by Staph bacteria. The goal was to see if the test could help doctors choose antibiotics that work better. 33 adults took part, and the study did not change their regular…

This study looked at whether people who inject opioids can safely finish a course of IV antibiotics at home instead of staying in the hospital. Ten participants received home antibiotic therapy along with addiction medication and support from a health coach and case manager. The …

This study looked at how staphylococcus bacteria on the skin affect inflammation and immune responses in people with moderate to severe atopic dermatitis (eczema). Researchers took skin biopsies and blood samples from 41 adults to measure bacterial toxins and immune cell activity…

This lab study tested whether levobupivacaine, a local anesthetic used in patient-controlled analgesia (PCA) pumps, can kill Staphylococcus aureus bacteria. Researchers mixed the drug at two common concentrations with bacteria in a lab model and counted how many bacteria survived…

This study tested whether having a study team call doctors with a checklist could improve how they manage patients with Staphylococcus aureus bloodstream infections. The calls reminded doctors of key steps like follow-up blood cultures, proper antibiotics, and imaging tests. The …

This study looked at 278 diabetic patients to see if the same staph bacteria found in their noses also appear in their foot ulcers. Researchers compared the genetic fingerprints of the bacteria to understand the link. The goal was to learn more about infection risks, not to test …