New drug shows promise against staph blood infections

NCT ID NCT05184764

Completed Disease control Sponsor: Armata Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new medicine called AP-SA02, given through a vein, along with standard antibiotics for adults with a Staph blood infection. The main goal was to check if the combination is safe and tolerable. Researchers also looked at whether it helped clear the infection faster. The study involved 56 participants and has been completed.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease with sepsis staphylococcal infection staphylococcus aureus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACTEREMIA BACTEREMIA DUE TO STAPHYLOCOCCUS AUREUS BACTEREMIA STAPH STAPHYLOCOCCUS AUREUS STAPHYLOCOCCUS AUREUS BACTEREMIA

Contacts and locations

Locations

Banner University Medical Center

Tucson, Arizona, 85719, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Froedtert Hospital and the Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Henry Ford Health System

Detroit, Michigan, 48202, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Johns Hopkins University

Baltimore, Maryland, 21218, United States
Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center

Torrance, California, 90502, United States
Methodist Hospital Research Institute - Houston

Houston, Texas, 77030, United States
Monash Health

Clayton, Australia
Montefiore Medical Center

The Bronx, New York, 10467, United States
Regional One Healthcare

Memphis, Tennessee, 38103, United States
Rhode Island Hospital

Providence, Rhode Island, 02903, United States
Rocky Mountain Regional VA Medical Center

Aurora, Colorado, 80045, United States
Royal Adelaide Hospital

Adelaide, Australia
Royal Melbourne Hospital

Melbourne, Australia
The Alfred Hospital

Melbourne, Australia
The Jamaica Hospital Medical Center

Jamaica, New York, 11418, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
University of California, Los Angeles (UCLA) - Medical Center

Los Angeles, California, 90095, United States
University of California, San Diego (UCSD) - Medical Center

La Jolla, California, 92037, United States
University of Florida (UF) - Division of Infectious Disease

Gainesville, Florida, 32610, United States
University of Florida - Jacksonville

Jacksonville, Florida, 32209, United States
University of Michigan

Ann Arbor, Michigan, 48103, United States
University of North Carolina - Chapel Hill School of Medicine

Chapel Hill, North Carolina, 27599, United States
University of South Florida

Tampa, Florida, 33620, United States
University of Southern California Keck School of Medicine

Los Angeles, California, 90033, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Westmead Hospital

Westmead, Australia

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