Virus vs. superbug: new weapon tested for dangerous blood infections

NCT ID NCT05184764

Summary

This study tested whether adding an experimental treatment called AP-SA02 to standard antibiotics helps adults hospitalized with a serious Staphylococcus aureus (Staph) blood infection. AP-SA02 is a type of virus that specifically attacks bacteria. The main goals were to see if the combination was safe and if it helped patients recover better than antibiotics alone.

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Contacts and locations

Locations

  • Banner University Medical Center

    Tucson, Arizona, 85719, United States

  • Emory University Hospital Midtown

    Atlanta, Georgia, 30308, United States

  • Froedtert Hospital and the Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21218, United States

  • Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center

    Torrance, California, 90502, United States

  • Methodist Hospital Research Institute - Houston

    Houston, Texas, 77030, United States

  • Monash Health

    Clayton, Australia

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Regional One Healthcare

    Memphis, Tennessee, 38103, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Rocky Mountain Regional VA Medical Center

    Aurora, Colorado, 80045, United States

  • Royal Adelaide Hospital

    Adelaide, Australia

  • Royal Melbourne Hospital

    Melbourne, Australia

  • The Alfred Hospital

    Melbourne, Australia

  • The Jamaica Hospital Medical Center

    Jamaica, New York, 11418, United States

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • University of California, Los Angeles (UCLA) - Medical Center

    Los Angeles, California, 90095, United States

  • University of California, San Diego (UCSD) - Medical Center

    La Jolla, California, 92037, United States

  • University of Florida (UF) - Division of Infectious Disease

    Gainesville, Florida, 32610, United States

  • University of Florida - Jacksonville

    Jacksonville, Florida, 32209, United States

  • University of Michigan

    Ann Arbor, Michigan, 48103, United States

  • University of North Carolina - Chapel Hill School of Medicine

    Chapel Hill, North Carolina, 27599, United States

  • University of South Florida

    Tampa, Florida, 33620, United States

  • University of Southern California Keck School of Medicine

    Los Angeles, California, 90033, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

  • Westmead Hospital

    Westmead, Australia

Conditions

Explore the condition pages connected to this study.