New Staph-Fighting skin regimen shows promise in High-Risk community

NCT ID NCT06210594

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a combination of topical antibiotics and antiseptic washes could reduce staph bacteria on the skin of Native American adults living on or near tribal lands. Participants were at high risk for staph infections due to diabetes, obesity, or recent infections. The trial compared the biomedical regimen plus education and household supplies to education and supplies alone, measuring staph carriage and infection rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Mupirocin (Bactroban) + Nozin + chlorhexidine gluconate (Hibiclens)
What this could lead to
If successful, this approach could reduce staph infections in high-risk communities by lowering the amount of staph bacteria on the skin.
What could go wrong
This is a small, completed Phase 4 trial with only 78 participants, so results may not apply to broader populations. The regimen requires ongoing use, and long-term adherence may be challenging.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Whiteriver Center for Indigenous Health

    Whiteriver, Arizona, 85941, United States

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