Tracking immune recovery after sepsis: clues to better outcomes

NCT ID NCT01879761

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study looks at how the immune system bounces back in people who survive a severe bloodstream infection caused by Staphylococcus aureus bacteria. Researchers are measuring specific immune markers, like HLA-DR on monocytes, to see if recovery differs between people with and without prior immune problems. The goal is to better understand why some patients develop new infections after sepsis and how to improve their care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors predict which sepsis patients are at higher risk for complications and tailor follow-up care.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to direct changes in patient care, and results may not apply to all sepsis patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Chicago Hospital

    Chicago, Illinois, 60637, United States

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