Spondylosis
MONDO:0002253A degenerative spinal disease that can involve any part of the vertebra, the intervertebral disk, and the surrounding soft tissue.
96 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New bone graft material for neck surgery under safety review
Disease control Not yet recruitingThis study looks back at medical records of 300 people who had neck spine fusion surgery using a special graft material called NMP®. The goal is to see how safe it is by checking for complications and whether patients needed another surgery within 90 days to 2 years. The research…
Sponsor: Red Rock Regeneration Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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New putty may help back surgery patients heal faster
Disease control Not yet recruitingThis study looks at a special putty called Fibergraft used in spine surgery to help bones grow together. About 80 adults with back pain or nerve problems from spine issues will get this putty during surgery. Doctors will check how well the bones heal using CT scans and ask patien…
Sponsor: AO Innovation Translation Center • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Spine surgeons test new CT technique to catch hidden instability during surgery
Diagnosis Not yet recruitingThis study looks at whether CT scans taken during lumbar spine surgery can detect spinal instability more reliably than standard X-rays taken before surgery. Researchers will review imaging and medical records from 100 adults undergoing surgery for degenerative spine conditions. …
Sponsor: 4th Military Clinical Hospital with Polyclinic, Poland • Aim: Diagnosis
Last updated Jun 27, 2026 13:06 UTC
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New pill aims to shield stomachs from common painkiller damage
Prevention Not yet recruitingThis study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. T…
Phase: PHASE4 • Sponsor: Daewoong Pharmaceutical Co. LTD. • Aim: Prevention
Last updated Jun 27, 2026 12:07 UTC
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Can a video call replace the physio clinic for neck pain?
Symptom relief Not yet recruitingThis study tests whether doing physiotherapy at home through live video calls works as well as going to a clinic for people with moderate neck pain from cervical spondylosis. Fifty-two adults aged 45-64 will be split into two groups: one gets in-person sessions, the other gets re…
Phase: NA • Sponsor: Lahore University of Biological and Applied Sciences • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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Freezing pain away: yale tests Nerve-Blocking procedure for Long-Term relief
Symptom relief Not yet recruitingThis study will follow 80 people with chronic pain (like back, hip, or nerve pain) who are getting a procedure called cryoneurolysis, which uses cold to temporarily block pain signals. Researchers want to see if it leads to meaningful pain relief and better daily function over 12…
Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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Ancient needle trick could ease stubborn neck pain without pills
Symptom relief Not yet recruitingThis study tests whether a specialized acupuncture technique called 'Three-Needle Dazhui' combined with electroacupuncture can reduce pain and improve daily function better than standard electroacupuncture alone. The trial will involve 74 adults with cervical spondylotic radiculo…
Phase: NA • Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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New needle angle could mean less back pain for millions
Symptom relief Not yet recruitingThis study tests two different methods of radiofrequency ablation (a procedure that uses heat to calm pain nerves) for people with long-term low back pain. The standard method uses a slight angle, while the new method places the needle more straight in from the back. Researchers …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Could a gentle ear zap boost pain relief for pinched nerves?
Symptom relief Not yet recruitingThis study tests whether a gentle electrical stimulation of the ear (taVNS) given before a standard epidural steroid injection can improve pain relief for people with cervical radiculopathy—a pinched nerve in the neck causing arm pain. Eighty adults will be randomly assigned to r…
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Hip stretches may ease back pain from slipped spine bone
Symptom relief Not yet recruitingThis study looks at whether a specific hip stretching technique can reduce back disability and pain in people with spondylolisthesis, a condition where a spine bone slips forward. Researchers will measure disability, pain, and how well the lower back bends. The study plans to inc…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Needle combo may ease stubborn back pain without drugs
Symptom relief Not yet recruitingThis study tests whether combining electroacupuncture (using mild electric pulses on needles) with ear acupressure (using small seeds on ear points) can reduce pain and improve function in people with chronic low back pain. 76 adults aged 40-70 with pain lasting at least 12 weeks…
Phase: NA • Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Neck pain sufferers: simple exercises may improve your balance
Symptom relief Not yet recruitingThis study tests whether a program of vestibular rehabilitation exercises can improve balance, reduce dizziness, and ease pain in people with cervical spondylosis (neck arthritis). Sixty-two adults aged 40 to 60 with chronic neck pain and balance issues will be assigned to either…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Can a simple injection speed up hip replacement recovery?
Symptom relief Not yet recruitingThis study looks at whether injecting platelet-rich plasma (PRP) into the sacroiliac joint after hip replacement surgery can help people recover faster and have less pain. About 60 adults with hip arthritis who are scheduled for a hip replacement will take part. Half will get the…
Phase: NA • Sponsor: Medical University of Warsaw • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Can moving your upper back or hips ease lower back pain?
Symptom relief Not yet recruitingThis study tests whether adding thoracic (upper back) or hip mobility exercises to standard core stabilization exercises can better reduce pain and disability in people with lumbar spondylosis (a type of arthritis in the lower spine). Sixty adults aged 40-60 with chronic low back…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Can your own blood and fat heal aching joints? new trial aims to find out
Symptom relief Not yet recruitingThis early-phase trial will test four orthobiologic treatments—PRP, bone marrow concentrate, hyaluronic acid, and nanofat—in 300 adults with various muscle, joint, tendon, or bone conditions. The goal is to see if these natural substances can reduce pain and improve joint functio…
Phase: EARLY_PHASE1 • Sponsor: PROREGEN • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Phone app may boost exercise for aching joints
Symptom relief Not yet recruitingThis study looks at whether a mobile app can help people with common pains (neck, shoulder, back, or knee) do their prescribed home exercises more regularly. About 30 adults will be split into two groups: one using the app and one doing traditional exercises. The goal is to see i…
Phase: NA • Sponsor: National Yang Ming Chiao Tung University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Can a specific acupuncture point ease stubborn neck pain?
Symptom relief Not yet recruitingThis study tests whether adding acupuncture at a specific point called Lieque (LU7) to standard electroacupuncture provides extra pain relief for people with cervical spondylosis, a common cause of chronic neck pain. 130 adults aged 40 and older will receive either the combined t…
Phase: NA • Sponsor: Nguyen Ngoc Doan Thuy • Aim: Symptom relief
Last updated Jun 26, 2026 12:48 UTC
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Tiny study asks: can spine specialists see the same thing on CT?
Knowledge-focused Not yet recruitingThis study checks how consistently six doctors can grade degeneration of the small joints in the spine (facet joints) using CT scans. It includes 12 patients and uses the Pathria scale. The goal is to see if the grading method is reliable, not to test a treatment.
Sponsor: Sklifosovsky Institute of Emergency Care • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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New urdu tool could help millions with muscle and joint pain
Knowledge-focused Not yet recruitingThis study aims to translate and adapt a widely used questionnaire for musculoskeletal problems into Urdu. Researchers will enroll 110 Urdu-speaking adults, including patients with muscle or joint issues and healthy volunteers. The goal is to create a validated tool to measure sy…
Sponsor: Riphah International University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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AI vs. doctor: which note do patients trust more?
Knowledge-focused Not yet recruitingThis study looks at how patients feel when reading their own medical notes. Some will read the original doctor's note, others will read a simpler version written by artificial intelligence. Researchers want to see if the AI summary changes how much patients trust their doctor or …
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Vibration exposure may harm Veterans' spines – new study investigates
Knowledge-focused Not yet recruitingThis study looks at how whole body vibration from military or civilian jobs (like flying helicopters or driving trucks) affects the spine health of 112 veterans aged 20-45. Researchers will use advanced MRI scans to see changes in the discs and bones of the spine, both right afte…
Phase: NA • Sponsor: Milwaukee VA Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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New digital tool aims to speed up return to work for those with muscle pain
Knowledge-focused Not yet recruitingThis study tests a decision support system called SmaRTWork to help people on sick leave due to muscle or back pain return to work. About 298 adults in Norway will either use the system or receive usual care. The main goal is to see if the tool helps them return to work sustainab…
Phase: NA • Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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New study to reveal balance differences in common back pain conditions
Knowledge-focused Not yet recruitingThis study will measure balance in 80 people with three types of chronic low back pain: lumbar spondylosis, spondylolisthesis, and disc prolapse. Participants will stand on a special platform (Biodex Balance System) under different conditions, like with eyes open or closed, to se…
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC