Schizophrenia 12
MONDO:0012054A schizophrenia that has material basis in a mutation on chromosome 1p36.2.
Also known as: SCZD12, schizophrenia 12, schizophrenia type 12, Sczd12, schizophrenia susceptibility locus, chromosome 1P-related
71 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New therapy aims to boost medication adherence in early psychosis
Disease control OngoingThis study tests a 10-session program called AIM-AT, which uses acceptance-based techniques to help people with recent-onset psychosis better understand their illness and stick to their medication. The trial involves 126 participants in Hong Kong and tracks their medication adher…
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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AI listens for signs of depression, autism, and more in your speech
Diagnosis ENROLLING_BY_INVITATIONThis study is testing whether artificial intelligence can analyze a person's speech to help diagnose mental health conditions like depression, anxiety, autism, and schizophrenia. Researchers will record 500 people speaking and compare the AI's predictions to standard clinical dia…
Sponsor: Psyrin Inc. • Aim: Diagnosis
Last updated Jun 26, 2026 12:40 UTC
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Can VR games sharpen the minds of people with mental illness?
Symptom relief OngoingThis study tests whether virtual reality (VR) brain exercises can help people with schizophrenia or bipolar disorder think more clearly and function better in daily life. 80 adults will either receive VR training twice a week for 12 weeks or continue their usual care. Researchers…
Phase: NA • Sponsor: Università degli Studi di Brescia • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Can VR and brain training quiet the voices? new study investigates
Symptom relief OngoingThis small pilot study tests whether adding brain-wave feedback (EEG) to virtual reality therapy helps people with schizophrenia better tolerate and reduce distressing auditory hallucinations. Thirty adults with schizophrenia who hear voices will receive either VR therapy alone o…
Phase: NA • Sponsor: University Hospital Bispebjerg and Frederiksberg • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Veterans with psychosis get new sleep hope: CBT-I trial targets insomnia
Symptom relief OngoingThis study tests whether a type of talk therapy called Cognitive Behavioral Therapy for Insomnia (CBT-I) can improve sleep and daily functioning in veterans who have both psychosis and insomnia. About 152 veterans are taking part. The goal is to see if better sleep leads to bette…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Exercise program for psychosis shows promise in small study
Symptom relief OngoingThis study tests whether a combined aerobic and strength training program is feasible for adults with psychotic disorders. Forty participants will exercise for about an hour per session. Researchers will measure how many complete the program and track changes in fitness and stren…
Phase: NA • Sponsor: Solli Distriktspsykiatriske Senter • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Which country handles mentally ill offenders better? a Head-to-Head study
Knowledge-focused OngoingThis study follows 600 mentally ill offenders in Italy and California over three years to compare two very different treatment systems. Italy uses community-based care, while California relies on long-term hospital stays. Researchers will track violence, recovery, and functioning…
Sponsor: University of Bari • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Can magnetic pulses unlock memory secrets in early psychosis?
Knowledge-focused OngoingThis study uses a noninvasive brain stimulation technique called TMS, combined with brain scans, to understand working memory problems in people with early psychosis. Twenty participants will receive both active and placebo TMS to see how it affects brain activity and memory perf…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Massive study aims to unlock secrets of depression, bipolar, and psychosis
Knowledge-focused ENROLLING_BY_INVITATIONThis study is collecting DNA, brain scans, and other biological samples from 2,000 people with major depression, bipolar disorder, or psychotic disorders, as well as healthy volunteers. The goal is to better understand the physical and genetic factors behind these conditions, whi…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC