Rheumatic heart disease
MONDO:0006955An autoinflammatory condition following an infection with Group A Beta Hemolytic Streptococcus (GABHS), in which the heart is attacked by antibodies formed in reaction to a recent GABHS infection. Chief anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords, all of which can result in valvular dysfunction.
Also known as: RHD, disease, rheumatic heart, heart disease, rheumatic, rheumatic carditis
13 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
Study tests simple support for kids with heart disease
Disease control CompletedThis study looked at ways to help children aged 5-20 with rheumatic heart disease take their regular antibiotics. Researchers compared having a case manager alone versus a case manager plus a peer support group. The goal was to see if the simpler approach works just as well to ke…
Phase: NA • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
-
Heart drug showdown: which protects the right ventricle better after valve surgery?
Disease control CompletedThis study tested two drugs, levosimendan and dobutamine, in 52 adults undergoing heart valve replacement. The goal was to see which one better preserves right ventricular function after surgery. Patients were randomly assigned to receive one of the drugs, and their heart functio…
Sponsor: Helwan University • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC