Heart drug showdown: which protects the right ventricle better after valve surgery?

NCT ID NCT07416331

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested two drugs, levosimendan and dobutamine, in 52 adults undergoing heart valve replacement. The goal was to see which one better preserves right ventricular function after surgery. Patients were randomly assigned to receive one of the drugs, and their heart function was measured using echocardiograms at several time points.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
levosimendan and dobutamine
What this could lead to
If one drug proves better, it could become the preferred choice to protect heart function during valve surgery.
What could go wrong
This is a small, single-center study with only 52 patients, so results may not apply to everyone. The drugs also have known side effects like low blood pressure or heart rhythm issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Helwan University

    Giza, 12566, Egypt

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Other studies related to the condition(s) this trial covers.