Could a gut bacteria transplant ease a rare lung disease?

This early-stage trial tests whether transplanting gut bacteria from healthy donors, along with antibiotics and fiber, is safe and feasible for people with pulmonary arterial hypertension (PAH), a condition of high blood pressure in the lungs. About 24 adults with PAH will be randomly assigned to receive the bacteria capsules with fiber, bacteria with a placebo, or placebos only. Researchers will track how well the donor bacteria take hold in the gut, monitor side effects, and look at early signs of impact on heart function, walking ability, and quality of life.