Retinal detachment

This study tests whether taking nicotinamide riboside (a vitamin B3-like supplement) can help preserve vision in people with a detached retina affecting the macula (central vision). Participants take the supplement or a placebo daily for 20 weeks, starting at diagnosis. The goal …

This study compares two techniques for removing silicone oil from the eye after retinal detachment repair. About 200 people who previously had silicone oil placed in their eye will be randomly assigned to one of two removal methods: a special vitrectomy machine or a spring-loaded…

This study tests a laser treatment called OSC/SS to prevent retinal detachment in people with Stickler Syndrome, a genetic condition that raises the risk of vision loss. About 500 children and adults will receive the procedure in one or both eyes and be followed for 5 years. Rese…

This study tests whether netarsudil eye drops can prevent proliferative vitreoretinopathy (PVR), a scarring condition that can cause retinal detachment surgery to fail. Researchers will check how much of the drug reaches the back of the eye and whether it is safe. The trial enrol…

This study compares two surgical systems used for combined cataract and vitrectomy eye surgeries. The UNITY VCS system is being tested against the CONSTELLATION system to see which one surgeons find more efficient in real-world operating rooms. About 180 adults needing combined e…

This study investigates whether optical and ultrasound biometry can reliably measure the eye's structures in people whose eyes have been filled with silicone oil after retinal detachment surgery. One hundred participants will have their eyes measured before and one month after su…

This study collects fluid and blood samples from 260 people with age-related macular degeneration, diabetic retinopathy, or retinal detachment, plus healthy controls. Researchers will analyze proteins in these samples to identify markers that could help diagnose or track these ey…

This study looks at whether using a liquid called perfluorocarbon (PFCL) during retinal detachment surgery changes how the retina shifts after reattachment. About 292 adults with a detached retina that affects central vision will be randomly assigned to surgery with or without PF…

This study looks at 100 people with uncomplicated retinal detachment who need surgery. Doctors will peel a thin membrane from the back of the eye either during the first surgery or later when silicone oil is removed. The goal is to see which timing leads to fewer complications.

This study is observing how blood flow at the back of the eye changes after a type of retinal detachment surgery called scleral buckling. Researchers hope these observations will help them better understand other eye diseases, such as age-related macular degeneration. The study w…

This study tests a high-resolution imaging system to see tiny structures in the eye that routine tools cannot detect. Researchers will scan 1,200 people with various eye conditions and healthy volunteers. The goal is to better understand diseases like glaucoma, diabetes, and reti…

This study tests a special microscope that takes live 3D images inside the eye during surgery. It aims to help surgeons see better when treating conditions like retinal detachment, macular holes, and cataracts. About 262 people will take part, including healthy volunteers and sur…