Could a common supplement protect eyesight after retinal detachment?

NCT ID NCT06587945

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether taking nicotinamide riboside (a vitamin B3-like supplement) can help preserve vision in people with a detached retina affecting the macula (central vision). Participants take the supplement or a placebo daily for 20 weeks, starting at diagnosis. The goal is to see if it helps retinal cells survive and recover after standard surgery.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
nicotinamide riboside (a dietary supplement)
What this could lead to
If it works, this could offer a simple, safe supplement to help preserve vision after retinal detachment surgery.
What could go wrong
This is a small, early-phase trial. The supplement may not improve vision outcomes, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre for Eye Research Australia

    RECRUITING

    East Melbourne, Victoria, 3002, Australia

  • Cerulea

    RECRUITING

    East Melbourne, Victoria, 3002, Australia

  • Dr David Fabinyi

    RECRUITING

    Geelong, Victoria, 3220, Australia

  • Dr David Sousa

    RECRUITING

    Geelong, Victoria, 3220, Australia

  • The Royal Victorian Eye and Ear Hospital

    RECRUITING

    East Melbourne, Victoria, 3002, Australia

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