Prosthesis-related infectious disease

This study compares a single-stage surgery using implants coated with an antibiotic-loaded hydrogel to the standard two-stage surgery for treating chronic hip prosthesis infections. The single-stage approach aims to remove the infected implant and place a new one in the same oper…

This study is testing whether using a disinfectant called TauroPace during heart device surgery can prevent infections. About 2300 patients having procedures like pacemaker placement or replacement are being followed for up to 12 months. The goal is to see if this approach reduce…

This study looks at whether a special team of doctors and nurses can treat adults with suspected infections at home, instead of sending them to the hospital. About 500 people will be randomly assigned to either standard hospital care or home-based care from a mobile response team…

This study compares two types of antibiotic-loaded bone cement used during hip fracture surgery to see which better prevents joint infections. About 7000 patients aged 60 and older with displaced femoral neck fractures will be included. Hospitals are randomly assigned to use eith…

This study looks at whether taking oral antibiotics for 6 extra days after getting a penile implant can lower the chance of infection. Researchers are following 800 men for one year after surgery. The goal is to see if this simple step reduces the need for another surgery to remo…

This study compares two methods to prevent infections during first-time penile implant surgery for erectile dysfunction. One group receives the standard antibiotic rinse, the other uses Irrisept, a simpler cleaning solution. Researchers will follow 200 men for one year after surg…

This study tested a special antimicrobial wash (taurolidine) to see if it can prevent infections from metal implants like plates, screws, and joint replacements after trauma surgery. 28 adults who needed these implants took part. The study compared infection rates to those report…

This study aimed to see if a computer could learn to predict how long a patient would stay in a home hospital program. Researchers planned to use data from past patients to train the computer. However, the study was withdrawn before any patients were enrolled, so no results are a…

This study looks at why people with bone cancer (skeletal sarcoma) get more infections after joint replacement surgery than those with arthritis. Researchers will collect tissue and blood samples from 40 patients to compare immune and bacterial factors. The goal is to understand …

This study looks at 120 adults getting a left ventricular assist device (LVAD) to see how often infections happen and how their immune system changes after surgery. The goal is to find what makes some patients more likely to get infections. This research does not test a new treat…

This study was designed to check the safety and performance of Refobacin Revision-3 Bone Cement when used in hip or knee revision surgeries. It aimed to track how often metal implants needed to be removed, any side effects, and changes in pain, function, and quality of life. Howe…

This study looks back at 351 patients who had epidural catheters or ports placed for pain management over 23 years. Researchers want to find out how often infections happen and what factors, like how long the device stays in or where it's placed, increase the risk. The goal is to…

This study looks at immune cells from people with autoimmune diseases (like lupus), people with infections, and healthy volunteers. Researchers want to understand how these cells differ and what makes them attack the body in autoimmune conditions. The study involves blood and bon…