Can a few extra pills prevent implant infections?

NCT ID NCT05100654

Ongoing Disease control Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether taking oral antibiotics for 6 extra days after getting a penile implant can lower the chance of infection. Researchers are following 800 men for one year after surgery. The goal is to see if this simple step reduces the need for another surgery to remove an infected implant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oral antibiotics (doxycycline, ciprofloxacin, augmentin, or bactrim)
What this could lead to: If successful, this could show that a short course of oral antibiotics after surgery helps prevent infections, potentially improving outcomes for men with penile implants.
What could go wrong: This is an early-phase study, so results are preliminary. The antibiotics may not reduce infection risk, and side effects like upset stomach or allergic reactions are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

erectile dysfunction prosthesis-related infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ERECTILE DYSFUNCTION PENILE PROSTHESIS INFECTION

Contacts and locations

Locations

University of Chicago

Chicago, Illinois, 60637, United States

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