Primary avascular necrosis
MONDO:0018379Also known as: primary AVN
38 clinical trials for this condition and its sub-types.
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Broader categories
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New hip replacement device put to the test in 288-Patient trial
Disease control Recruiting nowThis study is testing a new hip replacement system called the HIT Reverse Hip Replacement System. It is for people aged 50 to 75 who need a total hip replacement due to arthritis, joint damage, or other conditions. The goal is to see if the new system is as safe and effective as …
Phase: NA • Sponsor: Hip Innovation Technology • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Your own stem cells could rebuild a dying hip bone
Disease control Recruiting nowThis study tests a new way to treat early-stage avascular necrosis (bone death) of the hip. Doctors take a patient's own bone marrow stem cells, grow them on a special bone scaffold in the lab, and then implant this 'tissue-engineered bone' into the damaged area. The goal is to s…
Phase: NA • Sponsor: The First Affiliated Hospital of Xinxiang Medical College • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New hip implant aims to fix cartilage without replacement
Disease control Recruiting nowThis early study is testing a new device called the ReNew Hip Implant in 15 people aged 14 to 64 with hip cartilage damage from conditions like osteoarthritis or hip impingement. The implant is surgically placed to repair the cartilage. Researchers are checking if it is safe and …
Phase: NA • Sponsor: Cytex Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New hip implant under study for arthritis sufferers
Disease control Recruiting nowThis study is testing a new hip replacement system called Emphasys Hip Solutions in 30 people with hip osteoarthritis. Researchers will use special X-ray imaging to see how well the implant stays in place over two years. The goal is to make sure the implant is stable and works we…
Phase: NA • Sponsor: Canadian Radiostereometric Analysis Network • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Could your own bone marrow cells save your hip from collapse?
Disease control Recruiting nowThis study tests whether adding a patient's own concentrated bone marrow cells to a standard hip surgery (core decompression) can prevent the hip ball from collapsing and delay or avoid the need for a hip replacement. It includes 192 adults with early-stage osteonecrosis (before …
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New hip implant under study for safety and performance
Disease control Recruiting nowThis study is checking how well the Z1 Femoral Hip System works and how safe it is for people who need hip replacement surgery. About 150 adults with hip problems like arthritis or fractures will be followed for 2 years. The main goal is to see how many implants are still in plac…
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New hip implant under surveillance: will it last?
Disease control Recruiting nowThis study is tracking 550 adults aged 18–75 who receive the Medacta SMS femoral stem during total hip replacement. Researchers will monitor how long the implant lasts, how well the hip functions, patient satisfaction, and quality of life. The goal is to confirm the device's safe…
Sponsor: Medacta International SA • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Blood test could catch hip disease before It's too late
Diagnosis Recruiting nowThis study is looking for substances in the blood that can help doctors diagnose osteonecrosis of the femoral head (a condition where the hip bone dies) much earlier. Currently, many cases are missed or misdiagnosed. Researchers will collect blood from 300 people with suspected h…
Sponsor: The First Affiliated Hospital of Xinxiang Medical College • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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New painkiller cocktail could cut opioid use after hip surgery
Symptom relief Recruiting nowThis study tests whether a long-acting form of the anesthetic bupivacaine, combined with regular bupivacaine, can control pain better than the standard drug ropivacaine after hip replacement. Sixty adults with hip fractures or necrosis will receive one of the two treatments via a…
Phase: PHASE4 • Sponsor: Huazhong University of Science and Technology • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New navigation tech aims to improve hip replacement accuracy
Knowledge-focused Recruiting nowThis study looks at how well a non-invasive navigation system helps surgeons place the hip cup during total hip replacement. About 118 people with hip conditions like arthritis or hip dysplasia will take part. The goal is to see if the actual cup position matches the planned posi…
Phase: NA • Sponsor: DePuy Orthopaedics • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Thousands tracked for decades to see how hip implants hold up
Knowledge-focused Recruiting nowThis study follows 2500 people who have had hip replacement surgery with Corin implants. Researchers will check how long the implants last and how well they work over 10, 15, and 20 years. The goal is to gather safety and performance data, not to test a new treatment.
Sponsor: Corin • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Which wash heals hips best? new trial tests Povidone-Iodine vs chlorhexidine
Knowledge-focused Recruiting nowThis study compares two antiseptic washes used during hip replacement surgery to see which one helps wounds heal better. About 420 adults with hip osteoarthritis or avascular necrosis will be randomly assigned to receive either povidone-iodine or chlorhexidine wash after their ne…
Phase: NA • Sponsor: F. Johannes Plate • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC