Could your own bone marrow cells save your hip from collapse?

NCT ID NCT06123481

Recruiting now Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a patient's own concentrated bone marrow cells to a standard hip surgery (core decompression) can prevent the hip ball from collapsing and delay or avoid the need for a hip replacement. It includes 192 adults with early-stage osteonecrosis (before collapse) and compares the combination treatment to surgery alone over two years. The goal is to preserve the natural hip joint and reduce pain.

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Conditions

The condition(s) this trial relates to.

avascular necrosis of femoral head, primary, 1 bone disorder familial avascular necrosis of femoral head Legg-Calve-Perthes disease musculoskeletal system disorder Necrosis osteonecrosis Pathologic Processes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AVASCULAR NECROSIS OF THE FEMORAL HEAD OSTEONECROSIS OF THE FEMORAL HEAD

Contacts and locations

Locations

Cleveland Clinic
RECRUITING

Cleveland, Ohio, 441195, United States
Johns Hopkins University
RECRUITING

Baltimore, Maryland, 21224, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
NYU Langone Health Orthopedic Hospital
RECRUITING

New York, New York, 11016, United States
Sinai Hospital of Baltimore
RECRUITING

Baltimore, Maryland, 21215, United States
Stanford University
RECRUITING

Stanford, California, 94063, United States
University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Southern California
RECRUITING

Los Angeles, California, 90033, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22903, United States

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