Posterior leukoencephalopathy syndrome
MONDO:0044033An acute or subacute reversible condition characterized by headaches, mental status changes, visual disturbances, and seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment.
Also known as: PRES, Posterior reversible encephalopathy syndrome, RPLE, posterior reversible encephalopathy syndrome, reversible Posterior cerebral edema syndrome, reversible Posterior cerebral oedema syndrome, reversible Posterior leukoencephalopathy syndrome, reversible occipital parietal encephalopathy
31 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Long-acting HIV shot study aims to make prevention fairer for all
Disease control Not yet recruitingThis study looks at whether a long-acting injectable HIV prevention drug (cabotegravir) can be delivered fairly and effectively in NHS sexual health clinics. Researchers will follow 200 people taking the drug for 12 months, along with 20 healthcare professionals, to see how well …
Sponsor: Queen Mary University of London • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Pharmacy-Based PrEP could transform HIV prevention for young women in tanzania
Prevention Not yet recruitingThis study explores whether offering HIV prevention medication (PrEP) through pharmacies can help more young women aged 18-24 in Tanzania access and consistently use it. Researchers compare four different pharmacy-based service models to standard care, and later test cost-sharing…
Phase: NA • Sponsor: Mzumbe University - Centre of Excellence in Health Monitoring and Evaluation • Aim: Prevention
Last updated Jul 24, 2026 00:00 UTC
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App and home delivery aim to keep youth HIV-free
Prevention Not yet recruitingThis study tests a new way to help young people (ages 13-24) stick with PrEP, a medication that prevents HIV. Participants get PrEP delivered to a community spot (like home or a mobile van) and use a smartphone app for reminders and support. The goal is to see if this combo impro…
Phase: NA • Sponsor: Westat • Aim: Prevention
Last updated Jul 15, 2026 00:00 UTC
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New toolkit aims to boost PrEP access for youth in alabama and botswana
Prevention Not yet recruitingThis study looks at how to make HIV prevention pills (PrEP) easier for young people to get and keep using. Researchers will follow 1000 current or eligible PrEP users in Alabama and Botswana for 2 years. They will also create and test a decision-support toolkit to help patients a…
Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated Jun 27, 2026 14:02 UTC
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Coaching doctors to prevent HIV in teens: a new approach
Prevention Not yet recruitingThis study looks at whether a one-on-one coaching method called academic detailing can help pediatricians feel more comfortable prescribing PrEP, a daily pill that prevents HIV. Fifty doctors will take part in brief, interactive sessions with a trained educator. The goal is to se…
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Prevention
Last updated Jun 27, 2026 08:14 UTC
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New study checks if HIV prevention shots and contraceptives clash
Knowledge-focused Not yet recruitingThis study looks at how a long-acting injectable HIV prevention drug (CAB-LA) and hormonal birth control methods (like the shot or implant) affect each other in women. About 105 women who already use CAB-LA or no HIV prevention will join groups based on their contraceptive choice…
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Can a simple letter curb antibiotic overuse? BC study aims to find out
Knowledge-focused Not yet recruitingThis study evaluates a program that sends family doctors and nurse practitioners a confidential report comparing their antibiotic prescribing to peers, along with an educational summary. Over 7,600 practitioners in British Columbia will be randomly assigned to receive the report …
Phase: NA • Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Morning workouts may tame blood pressure in glaucoma patients
Knowledge-focused Not yet recruitingThis study looks at whether different types of exercise (like walking or strength moves) and timing (morning vs. evening) can safely lower blood pressure in people with glaucoma and high blood pressure. About 60 adults will try four exercise sessions, and their blood pressure and…
Phase: NA • Sponsor: KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New italian knee questionnaire aims to improve ACL recovery tracking
Knowledge-focused Not yet recruitingThis study aims to translate and validate the KOOS-ACL questionnaire for Italian-speaking patients who have had anterior cruciate ligament (ACL) reconstruction. Researchers will enroll 120 native Italian speakers aged 18 or older to test the accuracy and cultural relevance of the…
Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC