Please sign in to follow a disease.
Pleural empyema
MONDO:0018667The presence of pus in the thoracic cavity, between the visceral and parietal pleura.
Also known as: pleural empyema, pleural empyema (disease), abscess of thorax, empyema, purulent pleurisy, purulent pleuritis, pyothorax, thorax abscess
25 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
Could a simple antiseptic wash beat chest infections without surgery?
Disease control CompletedThis study tests whether washing the infected chest cavity with povidone-iodine (an antiseptic) helps adults with pleural empyema recover faster than using normal saline alone. Participants receive chest tube drainage plus daily irrigation with either povidone-iodine or saline. T…
Phase: PHASE2 • Sponsor: Alexandria University • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
-
Which antibiotics work best for lung infections? new study compares options
Disease control CompletedThis completed study looked at 80 people with empyema, a serious lung infection. Researchers compared two different antibiotic combinations to see which was safer and more effective. The goal is to help doctors choose the best treatment for this condition.
Phase: NA • Sponsor: Fayoum University • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
-
New Light-Measuring tool tested in cancer surgery
Disease control CompletedThis early-phase trial tested a light-measuring system used during photodynamic therapy (PDT) for people with malignant mesothelioma, non-small cell lung cancer, or other pleural cancers. Nine participants received the drug porfimer sodium, which becomes active when exposed to li…
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
-
Saline vs. drugs: a simpler way to treat lung infections?
Disease control CompletedThis study compared two treatments for pleural infection, a serious lung condition where infected fluid builds up. One group received standard fibrinolytic drugs (alteplase and DNase) to break down clots, while the other group received simple saline (salt water) irrigation to flu…
Phase: NA • Sponsor: National University of Malaysia • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
-
Could a tiny dose of muscle relaxant make lung scopes safer?
Symptom relief CompletedThis study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…
Phase: NA • Sponsor: Harbin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
-
How many biopsies are just right? study aims to improve pleural diagnosis
Knowledge-focused CompletedThis study looked at 104 patients to find the optimal number of tissue samples (biopsies) to take during a pleuroscopy, a procedure to examine the lining of the lungs. The goal was to see how many biopsies are needed to make a diagnosis and to get enough tissue for further testin…
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
-
Tiny study checks antibiotic levels in lung infection fluid
Knowledge-focused CompletedThis completed study looked at how the antibiotics amoxicillin and clavulanic acid get into the infected fluid around the lungs in people with pleural infections. Eleven adults with complicated infections had chest tubes placed and received the antibiotics. Researchers measured a…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
-
Surgery for tough lung infections: new study reveals key insights on drug resistance
Knowledge-focused CompletedThis study looked at 350 patients who had surgery (decortication) to treat severe lung infections called empyema, including cases caused by tuberculosis and drug-resistant bacteria. The goal was to understand the types of germs causing these infections and how they affect recover…
Sponsor: University of Health Sciences Lahore • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:09 UTC