Tiny study checks antibiotic levels in lung infection fluid

NCT ID NCT04350502

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how the antibiotics amoxicillin and clavulanic acid get into the infected fluid around the lungs in people with pleural infections. Eleven adults with complicated infections had chest tubes placed and received the antibiotics. Researchers measured antibiotic levels in the blood and pleural fluid to see if enough drug reaches the infection site.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
amoxicillin and clavulanic acid
What this could lead to
If successful, this could help doctors choose the right antibiotic doses for pleural infections, improving treatment.
What could go wrong
This is a very small, completed pharmacokinetic study with only 11 participants. It does not test whether the antibiotics actually improve outcomes, only how they distribute in the body.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AMOXICILLIN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Community-Acquired Pneumonia empyema pleural empyema pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Amiens

    Amiens, 80480, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.