Tiny study checks antibiotic levels in lung infection fluid

NCT ID NCT04350502

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This completed study looked at how the antibiotics amoxicillin and clavulanic acid get into the infected fluid around the lungs in people with pleural infections. Eleven adults with complicated infections had chest tubes placed and received the antibiotics. Researchers measured antibiotic levels in the blood and pleural fluid to see if enough drug reaches the infection site.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Amiens

    Amiens, 80480, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

amoxicillin and clavulanic acid

What this could lead to

If successful, this could help doctors choose the right antibiotic doses for pleural infections, improving treatment.

What could go wrong

This is a very small, completed pharmacokinetic study with only 11 participants. It does not test whether the antibiotics actually improve outcomes, only how they distribute in the body.

Conditions

The condition(s) this trial relates to.

Community-Acquired Pneumonia empyema pleural empyema pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.