Shorter h. pylori treatment put to the test: 10 days vs. 14 days
NCT ID NCT07720037
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This trial tests whether a 10-day course of high-dose vonoprazan plus amoxicillin can clear Helicobacter pylori infection as effectively as the standard 14-day regimen. Adults aged 18 to 70 with a current H. pylori infection and no prior treatment are randomly assigned to one of two groups. The main goal is to compare how well each treatment eradicates the bacteria, with follow-up testing after treatment ends.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- vonoprazan and amoxicillin
- What this could lead to
- If the shorter, higher-dose regimen works as well as the standard 14-day course, it could simplify treatment and reduce the time patients need to take medication for H. pylori.
- What could go wrong
- This is a phase 4 trial with 232 participants, so results may not apply to everyone. The shorter regimen might cause more side effects or fail to clear the bacteria in some patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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