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Could a simple chemical wash replace surgery for trapped lungs?

NCT ID NCT07713329

Completed Disease control Sponsor: Delta University for Science and Technology Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study tests whether injecting a diluted hydrogen peroxide solution or steroids into the chest can break up scar tissue and free a trapped lung, compared to a standard surgical scraping procedure (thoracoscopy). The trial enrolls adults aged 18-62 with a lung infection that has caused fluid pockets and adhesions. Success is measured by a combined score of lung expansion, diaphragm movement, and fluid drainage one week after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
intrapleural hydrogen peroxide or intrapleural corticosteroids
What this could lead to
If successful, this could offer a cheaper, simpler treatment for trapped lungs due to infection, reducing the need for specialized surgery.
What could go wrong
This is a small early-phase trial (36 people), so results may not apply broadly. Hydrogen peroxide in the chest carries risks like air embolism or tissue damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

empyema Pleural Effusion pleural empyema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLEURAL ADHESIONS PLEURAL EFFUSION PLEURAL EMPYEMA PLEURAL INFECTION

Contacts and locations

Locations

  • Delta university for science and technology

    Gamasa, 1234, Egypt

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