Keyhole surgery may beat standard care for chest infections

NCT ID NCT07550530

Not yet recruiting Disease control Sponsor: Università Politecnica delle Marche Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

The PROMPT study is testing whether an early keyhole procedure called medical thoracoscopy works better than current standard treatment (medicines to break up thick fluid) for people with pleural infection. About 170 patients will be randomly assigned to one of the two treatments. Researchers will see which approach results in fewer additional procedures within 30 days, as well as how quickly people recover and whether they experience any complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: medical thoracoscopy (keyhole procedure)
What this could lead to: If it works, this could point toward a better first-line treatment for pleural infection, reducing the need for repeat procedures and speeding recovery.
What could go wrong: This is a relatively small, early-stage study (170 patients) and the procedure is more invasive than standard care, so it may not prove superior or could carry higher risks like pain or complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PLEURAL INFECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Inflammation pleural disorder pleural empyema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLEURAL INFECTION PLEURAL INFECTIONS PLEURAL INFECTIONS AND INFLAMMATIONS

More trials for these conditions

Other studies related to the condition(s) this trial covers.