PLEURAL EFFUSION

This study tests whether using a special microscope (confocal laser endomicroscopy) during a chest camera procedure can better diagnose unexplained pleural disease. About 158 adults with fluid around the lungs that standard tests couldn't diagnose will be randomly assigned to get…

This study is looking for new biological markers in the fluid that builds up around the lungs (pleural effusion) in people with lung adenocarcinoma. Researchers will compare these markers between cancerous and non-cancerous fluid samples from 100 patients. The goal is to see if t…

This study is testing a new portable X-ray machine called Dynamic Digital Radiography (DDR) that takes 15 images per second to show how the lungs move and blood flows. Researchers at Brigham and Women's Hospital will use it on 230 ICU patients with various lung conditions to see …

This study tests whether giving medication once a day through a chest tube works as well as giving it twice a day for people with serious infections around the lungs. Participants are adults already in the hospital with a chest tube draining infected fluid. They will be randomly …

This study tests whether a smaller 16F chest drain causes less pain than the standard 24F drain after minimally invasive lung surgery. About 124 adults having a lung lobe or segment removed will be randomly assigned to one drain size. Pain levels while coughing will be measured o…

This study compares two ways of draining fluid from around the lungs in people with advanced cancer: one using suction (vacuum) and one using gravity. The goal is to see which method causes less chest pain during drainage. About 200 participants will be randomly assigned to one o…

This study tests two different breathing exercises in 40 children aged 5 to 16 who have fluid around their lungs (pleural effusion). One group will use a simple bubble-blowing device combined with deep breathing, while the other uses a standard spirometer. The goal is to see whic…

This study tests whether using virtual reality (VR) during a chest drain insertion can make the experience less painful and more tolerable. About 80 adults who need the procedure will be randomly assigned to receive VR distraction or standard care. Researchers will measure satisf…

This study looks at why people with pleural effusion (fluid around the lungs) feel short of breath. Researchers will measure breathing effort and breathlessness before and after fluid removal in 124 adults. The goal is to better understand the connection, not to test a new treatm…

This study compares two ways to diagnose cancer in people with fluid buildup around the lungs (pleural effusion). One method, thoracentesis, drains the fluid with a needle. The other, pleuroscopy, uses a tiny camera to look inside and take tissue samples. Researchers want to see …

This study tests whether an AI tool called LuAna helps doctors find lung problems in chest X-rays more accurately than doctors working alone. About 1,470 adults with breathing issues will have their X-rays read first by doctors, then with AI support. The goal is to see if AI boos…

This study looks at two methods to prevent small chest tubes from getting blocked in patients with pleural effusion (fluid around the lungs). One method uses only saltwater flushes, the other adds a heparin lock. The goal is to see which keeps the tube working longer. About 40 ad…