PLEURAL EFFUSION

This study looks at whether giving medication once a day through a chest tube is as effective as twice a day for treating serious infections around the lungs. About 270 adults hospitalized with pleural infections will be randomly assigned to receive either once-daily or twice-dai…

This study tests whether an AI tool can help doctors find lung issues like pneumonia or fluid buildup on chest X-rays. About 1,470 adults with breathing problems will have their X-rays read by doctors with and without AI support. The goal is to see if AI improves detection rates …

This study tests whether a special microscope (confocal laser endomicroscopy) can help doctors take more accurate tissue samples from the lining of the lungs during a procedure called thoracoscopy. About 158 adults with unexplained fluid buildup around the lungs will be randomly …

This study tests a new portable X-ray machine that takes moving images of the lungs at the bedside in the ICU. It aims to see if this technology can give doctors better information about lung function and blood flow compared to standard X-rays. About 230 adults with various lung …

This study looks at two ways to drain fluid from around the lungs in people with advanced cancer. The goal is to see which method—gravity or suction—causes less chest pain during drainage. About 200 adults who need a drainage tube will be randomly assigned to one method and repor…

This study tests two types of breathing exercises in 40 children aged 5 to 16 who have fluid around their lungs (pleural effusion). One group will use a bubble device with special breathing techniques, and the other will use a standard spirometer. The goal is to see which method …

This study tests whether using a smaller chest drain (16F) instead of the usual larger one (24F) can reduce pain after minimally invasive lung surgery for cancer. About 124 adults having a lung lobe or segment removed will be randomly assigned to one drain size. Pain levels while…

This study tests whether using virtual reality (VR) goggles during a chest drain insertion can make the experience less painful and more tolerable. About 80 adults needing the procedure will be randomly assigned to receive standard care or standard care plus VR distraction. Resea…

This study looks at whether using a heparin lock after flushing with normal saline keeps small chest tubes (used to drain fluid from around the lungs) from getting blocked better than flushing alone. About 40 adults with pleural effusion will take part. The goal is to find the be…

This study compares two procedures—thoracentesis (draining fluid) and pleuroscopy (taking a tissue sample)—to see which one helps diagnose cancer in the chest faster. About 98 adults with suspected cancer-related fluid buildup will be randomly assigned to one procedure first. The…

This study looks for new molecular markers in the fluid that builds up around the lungs (pleural effusion) of people with lung adenocarcinoma. Researchers will compare these markers between cancerous and non-cancerous fluid samples from 100 patients. The goal is to find better wa…