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Pleural disorder
MONDO:0002037A non-neoplastic or neoplastic disorder that affects the pleura. Representative examples include pleural infection, pleural mesothelioma, and pleural solitary fibrous tumor.
Also known as: disease of pleura, disease or disorder of pleura, disorder of pleura, pleura disease, pleura disease or disorder, pleural disorder, pleural disorders, non-neoplastic pleural disease
163 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Mesothelioma radiation trial ends early – few answers found
Disease control TerminatedThis study looked at whether adding targeted radiation therapy to surgery and chemotherapy could help people with early-stage pleural mesothelioma live longer. Only 16 people took part before the trial was stopped early, so we don't have clear results. The approach aimed to kill …
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Light therapy boosts immune attack on lung cancer? early trial halted
Disease control TerminatedThis early-phase trial tested whether a light-activated drug (photodynamic therapy) could help immunotherapy work better in patients with non-small cell lung cancer that has spread to the lining of the lung or with mesothelioma. Only 5 people took part, and the study was stopped …
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Experimental combo for rare lung cancer shows early promise but trial halted
Disease control TerminatedThis early-phase trial tested the drug pembrolizumab (Keytruda) combined with targeted radiation (SBRT) in 5 people with advanced malignant pleural mesothelioma, a rare cancer of the lung lining. The goal was to check safety and find the right dose. The study was terminated early…
Phase: PHASE1 • Sponsor: Royal Marsden NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Immunotherapy combo studied for rare lung cancer, trial stopped early
Disease control TerminatedThis study tested two immunotherapy drugs, durvalumab and tremelimumab, in people with malignant pleural mesothelioma, a rare cancer of the lung lining. The trial enrolled 19 participants whose cancer had worsened after standard chemotherapy. The goal was to see if the drug combi…
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Experimental lung cancer combo trial ends early
Disease control TerminatedThis phase 2 trial tested a new drug called THOR-707 (Pegenzileukin) combined with other cancer treatments, including pembrolizumab, in 106 people with advanced lung cancer or pleural mesothelioma. The goal was to see if the combination could shrink tumors. However, the study was…
Phase: PHASE2 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Mesothelioma drug trial halted early – what we know
Disease control TerminatedThis phase 2 trial tested whether the drug nintedanib could help people with malignant pleural mesothelioma keep their cancer from growing after initial chemotherapy. 37 patients were randomly assigned to receive either nintedanib or a placebo twice daily. The study was terminate…
Phase: PHASE2 • Sponsor: European Organisation for Research and Treatment of Cancer - EORTC • Aim: Disease control
Last updated Jun 26, 2026 18:48 UTC
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Could a bronchoscope replace X-Rays for pneumothorax?
Diagnosis TerminatedThis study tested whether the ultrasound tip of an EBUS bronchoscope, placed on the chest, can detect pneumothorax (collapsed lung) as well as a standard ultrasound probe. Researchers enrolled 17 patients, including those with and without pneumothorax. The goal was to see if this…
Sponsor: University of Oklahoma • Aim: Diagnosis
Last updated Jun 27, 2026 12:02 UTC