Mesothelioma radiation trial ends early – few answers found

NCT ID NCT04158141

Terminated Disease control Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study looked at whether adding targeted radiation therapy to surgery and chemotherapy could help people with early-stage pleural mesothelioma live longer. Only 16 people took part before the trial was stopped early, so we don't have clear results. The approach aimed to kill remaining cancer cells after surgery, but the small number of participants limits what we can learn.

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Conditions

The condition(s) this trial relates to.

malignant pleural mesothelioma mesothelioma Mesothelioma, Malignant pleural biphasic mesothelioma pleural epithelioid mesothelioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLEURAL BIPHASIC MESOTHELIOMA PLEURAL EPITHELIOID MESOTHELIOMA STAGE I PLEURAL MALIGNANT MESOTHELIOMA AJCC V8 STAGE IA PLEURAL MALIGNANT MESOTHELIOMA AJCC V8 STAGE IB PLEURAL MALIGNANT MESOTHELIOMA AJCC V8 STAGE II PLEURAL MALIGNANT MESOTHELIOMA AJCC V8 STAGE IIIA PLEURAL MALIGNANT MESOTHELIOMA AJCC V8

Contacts and locations

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Locations

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

Houston, Texas, 77030, United States
MD Anderson West Houston

Houston, Texas, 77079, United States
MD Anderson in Sugar Land

Sugar Land, Texas, 77478, United States
MD Anderson in The Woodlands

Conroe, Texas, 77384, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122, United States
UM Sylvester Comprehensive Cancer Center at Coral Gables

Coral Gables, Florida, 33146, United States
UT MD Anderson - League City

League City, Texas, 77573, United States
UT MD Anderson Cancer Center

Houston, Texas, 77030, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States

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