Familial spontaneous pneumothorax
MONDO:0008259Familial spontaneous pneumothorax is a rare, genetic pulmonary disease characterized by the uni- or bilateral accumulation of air in the pleural cavity in persons with a positive family history and no underlying lung disease or previous chest trauma. Patients typically present dyspnea associated with acute onset of sharp and steady pleutiric chest pain of variable severity (which resolves within 24h even though pneumothorax is still present). Reflex tachycardia and/or respiratory or circulatory compromise may be observed. Other syndromes (e.g. Birt-Hogg-Dube, Marfan or Ehlers-Danlos syndromes) may be associated.
Also known as: Psp, pneumothorax, primary spontaneous, primary spontaneous pneumothorax, spontaneous pneumothorax
21 clinical trials for this condition and its sub-types.
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Smart chest tube may speed recovery for kids with lung air leaks
Symptom relief Recruiting nowThis study tests whether a digital chest tube system (Thopaz+) works better than the standard analog system for children who need a chest tube after lung surgery or a collapsed lung. The digital system measures air leaks precisely and keeps steady suction, which may shorten how l…
Phase: NA • Sponsor: University of Oklahoma • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Can magnetic pulses ease frontotemporal dementia?
Symptom relief Recruiting nowThis study is testing whether a safe, non-invasive brain stimulation technique called rTMS can help people with frontotemporal dementia (FTLD) or those at risk. 120 participants will receive either real or placebo stimulation for 2 weeks, then all will get real stimulation. Resea…
Phase: NA • Sponsor: Università degli Studi di Brescia • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Can a simple breath test diagnose diseases in children?
Knowledge-focused Recruiting nowThis study aims to see if analyzing the chemicals in a child's breath can help diagnose and monitor diseases like asthma, neurological disorders, and type 1 diabetes. Researchers will collect breath samples from up to 3,600 children and teens to find patterns linked to these cond…
Sponsor: University Children's Hospital Basel • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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DNA hunt for rare brain disease genes begins
Knowledge-focused Recruiting nowThis study collects DNA from up to 1,000 adults with progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), multiple system atrophy (MSA), or related conditions, plus their family members. Researchers will sequence participants' whole genomes to find genetic variants …
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC