Pilonidal sinus

This study tests a new radiofrequency treatment for infected pilonidal sinus, a painful skin condition common in young adults. The procedure uses heat to destroy diseased tissue, aiming to heal faster than traditional open surgery. Sixty participants will be followed for 6 months…

This trial compares four different surgical techniques for treating pilonidal sinus, a painful skin condition near the tailbone, in adolescents aged 12 to 18. The goal is to find which method causes the least pain, fewest complications, and lowest chance of the sinus coming back.…

This study compares two rinses used during surgery for pilonidal disease, a chronic skin condition near the tailbone. One rinse is Irrisept, an antiseptic that kills bacteria, and the other is normal saline, the standard rinse. The goal is to see if Irrisept reduces infections an…

This study compares two minimally invasive treatments for pilonidal sinus disease: phenol injection and laser ablation. Researchers will track complications, hospital stay, and recovery time in 64 adults with uncomplicated pilonidal sinus. The goal is to find which method is safe…

This study tests a cream called clascoterone on people with pilonidal disease, a skin condition in the buttock crease. For 12 weeks, participants apply the cream or a placebo twice daily. Researchers check if the cream improves disease severity and symptoms. The trial involves 75…

This study looks at whether a special 1940 nm laser can improve healing after pilonidal cyst surgery. About 30 adults who had the laser procedure will be checked one month later to see if the wound is fully closed without needing a bandage. The goal is to reduce pain and prevent …

This pilot study is testing whether laser hair removal can reduce the chance of pilonidal disease coming back in people with darker skin (Fitzpatrick types IV-VI). The study will enroll 36 people aged 10-21 who have had pilonidal disease. Participants will receive either standard…

This study tests a standardized cleft lift operation for people with complex or recurrent pilonidal sinus disease, a painful skin condition near the tailbone. Researchers want to see if this approach leads to faster wound healing and quicker return to daily activities compared to…

This study looks at the best way to clean wounds during surgery for advanced pilonidal disease. It compares standard saline to a special solution called hypochlorous acid to see which helps wounds close faster. About 72 people having surgery for stage 3 pilonidal disease will tak…

This study compares two standard local anesthesia methods—conventional and tumescent—for laser treatment of pilonidal sinus. 100 participants will report their pain levels on days 1, 2, and 7 after surgery using a simple 1-10 scale. The goal is to find which technique leads to le…

This study looks at how chronic perianal conditions like fistulas and abscesses impact a person's sexual health and body image—something often overlooked by doctors. Researchers will survey 60 adults using questionnaires to measure these effects and identify gaps in communication…

This study follows 240 adults who get laser surgery for pilonidal cysts, a painful skin condition near the tailbone. Researchers will check if the cyst comes back within two years by asking patients questions. The goal is to understand how effective laser treatment is over time.

This observational study follows 800 adults who receive Myriad™ during soft tissue reconstruction for wounds like abdominal dehiscence, pressure injuries, or anal fistulas. Researchers track healing time, complications, and side effects to understand how well the material works i…

This study follows 250 adults undergoing routine surgery for pilonidal sinus disease to understand why some wounds reopen. Researchers will track the sinus's distance from the anus, the disease stage, and the surgical method used. The goal is to identify factors that lead to woun…

This study follows 100 people whose pilonidal cyst came back after either surgery or laser treatment. Researchers will use questionnaires to measure how the recurrence impacts quality of life, pain, and daily activities. The goal is to better understand the real-world burden of t…