Laser vs. phenol: which minimally invasive treatment hurts less?

NCT ID NCT07701772

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Sep 02, 2026 · Updated 3 times

Summary

This trial compares two minimally invasive procedures—laser ablation and crystallized phenol application—for treating primary uncomplicated pilonidal sinus disease. Adults with this condition are randomly assigned to one of the two treatments. The main goal is to measure pain on the first day after the procedure, with additional outcomes including wound healing time and recurrence at six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
laser ablation or crystallized phenol application
What this could lead to
If one method proves less painful and faster to heal, it could become the preferred minimally invasive treatment for pilonidal sinus disease.
What could go wrong
This is a single-center trial with 120 participants, so results may not apply broadly. Both treatments carry risks of infection or recurrence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Diagnosis of primary chronic sacrococcygeal pilonidal sinus disease * Uncomplicated disease * Suitability for minimally invasive treatment * Provision of written informed consent Exclusion Criteria: * Acute pilonidal abscess * History of pilonidal abscess drainage * Previous surgical or interventional treatment for pilonidal sinus disease * Recurrent pilonidal disease * Complex pilonidal disease or marked lateral extension * Immunosuppression, chronic steroid use, or systemic conditions that may significantly impair wound healing * Inability to attend regular follow-up * Refusal to participate in the study

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative pilonidal sinus Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sanliurfa Education and Research Hospital

    RECRUITING

    Sanliurfa, Şanlıurfa, Turkey (Türkiye)

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