Periodontal disorder
MONDO:0002635An inflammatory process of the gingival tissues and/or periodontal membrane of the teeth, resulting in an abnormally deep gingival sulcus, possibly producing periodontal pockets and loss of alveolar bone support.
Also known as: disease of periodontium, disease or disorder of periodontium, disorder of periodontium, periodontal disease, periodontal disorder, periodontium disease, periodontium disease or disorder
802 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Gum graft showdown: synthetic vs. natural tissue in recession repair
Disease control TerminatedThis study tested whether a synthetic gum graft (Mucogain matrix) could be a good alternative to the standard connective tissue graft for treating receding gums. The goal was to see if the synthetic option covers the exposed tooth root just as well, but with less pain and fewer c…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Probiotics and brushing: a tiny study on gum health in teens with braces ends early
Disease control TerminatedThis study looked at whether taking probiotic tablets (Lactobacillus reuteri) twice a day, along with regular tooth brushing, could reduce gum inflammation in teenagers with braces. Only 3 participants were enrolled before the study was terminated early, so no meaningful results …
Phase: NA • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Tooth rebuild before gum graft: does it help cover exposed roots?
Disease control TerminatedThis study looked at 15 people with gum recession and worn-down teeth near the gum line. Some had the worn area rebuilt with a tooth-colored filling before standard gum surgery, while others had surgery alone. The goal was to see if rebuilding the tooth first leads to better cove…
Phase: NA • Sponsor: Gonzalo Blasi • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Laser zaps root canal bacteria in new study
Disease control TerminatedThis study tested whether a special laser (Er,Cr:YSGG) can kill bacteria in root canals better than the standard rinse. 56 adults undergoing root canal treatment had their canals cleaned with either the laser or standard sodium hypochlorite. Researchers measured bacterial levels …
Phase: NA • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Gum treatment may slow memory loss in seniors
Prevention TerminatedThis study looked at whether intensive treatment for gum disease (periodontitis) could prevent dementia in older adults who already have mild cognitive impairment and narrowed neck arteries. Participants received either standard dental care or deep cleaning and root planing. The …
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Prevention
Last updated Jun 27, 2026 09:06 UTC
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Scientists gather leftover surgical tissue to unlock secrets of bone disease
Knowledge-focused TerminatedThis study collected bone, cartilage, skin, and fat tissue from 50 patients undergoing surgery at Children's National Medical Center. The goal was to grow cells from these tissues in the lab and analyze them to better understand bone and connective tissue diseases. The study was …
Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC