Laser zaps root canal bacteria in new study

NCT ID NCT05959629

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special laser (Er,Cr:YSGG) can kill bacteria in root canals better than the standard rinse. 56 adults undergoing root canal treatment had their canals cleaned with either the laser or standard sodium hypochlorite. Researchers measured bacterial levels before and after treatment and also checked pain levels. The study was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Er,Cr:YSGG laser (Waterlase Express™)

What this could lead to

If successful, this laser method could become a new option to disinfect root canals, potentially reducing infection and pain after treatment.

What could go wrong

This was a small, early study that was terminated, so results are limited. The laser may not work better than standard care, and its effectiveness is not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ROOT CANAL INFECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

dental abscess dental pulp disorder suppurative periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pennsylvania, School of Dental Medicine

    Philadelphia, Pennsylvania, 19104, United States