Periapical granuloma
MONDO:0006897Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment.
24 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Smartphone AI could spot gum disease with a single photo
Diagnosis CompletedThis study tests an artificial intelligence system that measures the width of keratinized gingiva (a type of gum tissue) from smartphone photos. Researchers will compare the AI's measurements to those made by dental experts to see how accurate the tool is. The goal is to make gum…
Sponsor: Al-Azhar University • Aim: Diagnosis
Last updated Jul 10, 2026 00:00 UTC
-
Precision dental surgery boosts healing and comfort
Symptom relief CompletedThis study tested a more precise dental surgery for people with persistent root infections after standard treatment. Using a 3D-printed guide, surgeons aimed to remove infected tissue more accurately, reduce surgery time, and improve quality of life. The trial involved 70 adults …
Phase: NA • Sponsor: Postgraduate Institute of Dental Sciences Rohtak • Aim: Symptom relief
Last updated Jul 30, 2026 00:00 UTC
-
Could the timing of your period change how much a dental cleaning hurts?
Symptom relief CompletedThis study asks whether the phase of the menstrual cycle influences pain and anxiety during a deep dental cleaning in premenopausal women with moderate gum disease. Researchers will compare pain scores and anxiety levels when treatment is done just before or just after menstruati…
Sponsor: Karadeniz Technical University • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
-
Could a cold rinse and diabetes drug soothe root canal pain?
Symptom relief CompletedThis study tested whether rinsing the tooth with cold saline (cryotherapy) or placing metformin (a diabetes drug) inside the tooth can reduce pain after root canal treatment. 80 adults with infected lower premolars were randomly assigned to receive one of four treatments. Pain wa…
Phase: PHASE2 • Sponsor: Celalettin Topbaş • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
-
Coffee drinkers: your morning cup may impact your gums!
Knowledge-focused CompletedThis study examined 318 adults to see if coffee drinking habits are linked to gum health. Participants were grouped by gum condition (healthy, gingivitis, or periodontitis) and asked about their coffee intake. Researchers measured plaque, bleeding, and gum pocket depth to find an…
Sponsor: Tuğba ŞAHİN • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
-
Gum health tied to dental Know-How in new turkish study
Knowledge-focused CompletedThis completed study looked at 108 Turkish adults to see if understanding dental health information is linked to gum health. Participants took a reading test about dentistry and had a dental exam. The goal was to find out if people with lower health literacy have worse gum diseas…
Sponsor: Biruni University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
-
Smoking linked to worse gum health in new study
Knowledge-focused CompletedThis completed study looked at how smoking affects gum health in 484 adults. Researchers compared current smokers to non-smokers by measuring plaque, gum bleeding, pocket depth, and gum recession. The goal was to better understand the link between smoking and periodontal disease.
Sponsor: Tuğba ŞAHİN • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC