Chill out tooth pain: cold wash and diabetes drug ease root canal ache
NCT ID NCT07437612
First seen Feb 28, 2026 · Last updated May 02, 2026 · Updated 8 times
Summary
This study tested whether using cold saline (cryotherapy) and the diabetes drug metformin inside the tooth could lower pain after root canal treatment. 80 adults with infected teeth were split into four groups, receiving either standard medicine, metformin, cold therapy plus standard medicine, or cold therapy plus metformin. Patients rated their pain daily for a week to see which approach worked best.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Saglik Bilimleri University
Istanbul, Turkey (Türkiye)
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