Chill out tooth pain: cold wash and diabetes drug ease root canal ache
Symptom relief
Completed
This study tested whether using cold saline (cryotherapy) and the diabetes drug metformin inside the tooth could lower pain after root canal treatment. 80 adults with infected teeth were split into four groups, receiving either standard medicine, metformin, cold therapy plus stan…
Phase: PHASE2 • Sponsor: Celalettin Topbaş • Aim: Symptom relief
Last updated May 04, 2026 16:20 UTC