Ovarian endometriosis

This study compares three surgical treatments for endometriomas (ovarian cysts from endometriosis) in 332 women aged 18-43 who want to become pregnant. Participants are randomly assigned to cystectomy, plasma vaporization, or sclerotherapy. The main goal is to see which approach …

This study looks at a treatment for large ovarian cysts caused by endometriosis (6 cm or bigger). The approach involves draining the cyst during a keyhole surgery and then using hormone therapy to lower the chance of the cyst coming back and to protect the ovaries. The goal is to…

This study compares two surgical methods for treating ovarian endometriomas (cysts caused by endometriosis): standard cystectomy (removing the cyst wall) and argon plasma coagulation (using a gas-based tool to destroy the cyst lining). The goal is to see which method better prese…

This study tests if injecting alcohol into endometriosis-related ovarian cysts (sclerotherapy) can better preserve egg supply and reduce cyst return compared to standard surgical removal. Sixty women aged 18-40 with cysts at least 2 cm will be randomly assigned to one of the two …

This study tests whether ultrasound-guided alcohol sclerotherapy can reduce pelvic pain and improve quality of life in women aged 18-45 with ovarian endometriomas. Participants are randomly assigned to receive the procedure or no treatment (expectant management) and are followed …

This study tests whether injecting the local anesthetic bupivacaine into the small surgical cuts and the vaginal cuff at the end of a laparoscopic hysterectomy can lower postoperative pain. 120 women having the surgery for non-cancer reasons will be randomly assigned to receive t…

This study at the National Institutes of Health is looking at 1,000 adults with known or suspected hormone gland (endocrine) disorders. The goal is to better understand these conditions and help train doctors. Participants may receive tests, treatments, or surgery as part of thei…

This study enrolls up to 15,000 children with known or suspected endocrine or metabolic disorders, along with their family members. Researchers will collect medical records, blood, saliva, and other samples to identify genetic changes linked to these conditions. The goal is to be…

This study enrolls adults with known or suspected endocrine (hormone gland) disorders, such as diabetes or thyroid disease, to help researchers learn more about these conditions. Participants will undergo medical exams, blood and imaging tests, and possibly genetic testing. The m…

This study is testing a tool called B-COMPASS that uses a 22-question survey to predict whether people will follow their prescribed treatments. Researchers will enroll 3100 adults with cardiovascular, endocrine, immune, nerve, cancer, or rare diseases across Europe. The goal is t…

This study is creating a huge collection of ultrasound images from the uterus and ovaries. Researchers will gather scans from 25,000 women, both healthy and with gynecological conditions, during routine checkups. The goal is to build a database that doctors and artificial intelli…

This study looks at how the uterus absorbs fluid during early pregnancy, which may affect fertility. Researchers will compare tissue samples from women with and without endometriosis or infertility. The goal is to understand the role of certain proteins in this process. No treatm…

This study looks at whether MRI scans can help doctors predict which women with endometriosis will benefit from the drug dienogest. Researchers will follow 48 women aged 19-45 who are starting dienogest for the first time. By comparing MRI images before treatment with changes in …

This study compares two approaches after robotic hysterectomy: going home the same day versus staying overnight in the hospital. Researchers will track quality of life and complications over 30 days in 300 patients with benign conditions or endometrial cancer. The goal is to see …

This study tests a surgical tool called CUSA Clarity that uses ultrasound to selectively remove endometriosis cyst lining while leaving healthy ovary tissue intact. Researchers will examine cyst wall samples from 10 women to see if the tool can spare ovarian tissue, which may hel…