Ovarian endometriosis
MONDO:0006337A non-neoplastic disorder characterized by the growth of endometrial tissue in the ovaries. It results in the development of blood filled ovarian cysts (chocolate cysts), and creation of scars and adhesions.
Also known as: endometriosis (disease) of ovary, endometriosis of ovary, ovarian endometriosis, ovary endometriosis (disease)
22 clinical trials for this condition and its sub-types.
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Which surgery helps women with endometriomas get pregnant faster?
Disease control Recruiting nowThis study compares three surgical treatments for endometriomas (ovarian cysts from endometriosis) in 332 women aged 18-43 who want to become pregnant. Participants are randomly assigned to cystectomy, plasma vaporization, or sclerotherapy. The main goal is to see which approach …
Phase: NA • Sponsor: Clinique Tivoli Ducos • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Draining cysts plus hormones may protect fertility in endometriosis
Disease control Recruiting nowThis study looks at a treatment for large ovarian cysts caused by endometriosis (6 cm or bigger). The approach involves draining the cyst during a keyhole surgery and then using hormone therapy to lower the chance of the cyst coming back and to protect the ovaries. The goal is to…
Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New study tests gentler surgery for ovarian cysts
Disease control Recruiting nowThis study compares two surgical methods for treating ovarian endometriomas (cysts caused by endometriosis): standard cystectomy (removing the cyst wall) and argon plasma coagulation (using a gas-based tool to destroy the cyst lining). The goal is to see which method better prese…
Phase: NA • Sponsor: Erbe Elektromedizin GmbH • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New injection could save ovaries in endometriosis cyst surgery
Disease control Recruiting nowThis study tests if injecting alcohol into endometriosis-related ovarian cysts (sclerotherapy) can better preserve egg supply and reduce cyst return compared to standard surgical removal. Sixty women aged 18-40 with cysts at least 2 cm will be randomly assigned to one of the two …
Phase: NA • Sponsor: Chelsea and Westminster NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Could a simple alcohol injection ease endometrioma pain?
Symptom relief Recruiting nowThis study tests whether ultrasound-guided alcohol sclerotherapy can reduce pelvic pain and improve quality of life in women aged 18-45 with ovarian endometriomas. Participants are randomly assigned to receive the procedure or no treatment (expectant management) and are followed …
Phase: NA • Sponsor: Hospital Universitari de Bellvitge • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Simple injection may ease pain after hysterectomy surgery
Symptom relief Recruiting nowThis study tests whether injecting the local anesthetic bupivacaine into the small surgical cuts and the vaginal cuff at the end of a laparoscopic hysterectomy can lower postoperative pain. 120 women having the surgery for non-cancer reasons will be randomly assigned to receive t…
Phase: NA • Sponsor: Serkan Kumbasar • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Measuring the heat: how a surgical tool affects ovarian tissue in endometriosis
Knowledge-focused Recruiting nowThis study looks at how deeply argon beam coagulation (a tool that uses ionized gas to seal tissue) penetrates the ovary during laparoscopic surgery for ovarian endometriomas. Researchers will apply the technique to the cyst surface before removing it, then examine the tissue und…
Phase: NA • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Surgery's hidden toll: which ovarian cysts pose greater risk to fertility?
Knowledge-focused Recruiting nowThis study compares how laparoscopic removal of ovarian cysts affects ovarian reserve—a key measure of fertility potential—in women with endometriotic cysts versus non-endometriotic cysts. Researchers will measure levels of anti-Müllerian hormone (AMH) before and three months aft…
Phase: NA • Sponsor: Benha University • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Scientists probe uterine fluid absorption to unlock fertility secrets
Knowledge-focused Recruiting nowThis study looks at how the uterus absorbs fluid during early pregnancy, which may affect fertility. Researchers will compare tissue samples from women with and without endometriosis or infertility. The goal is to understand the role of certain proteins in this process. No treatm…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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MRI may help predict endometriosis drug success
Knowledge-focused Recruiting nowThis study looks at whether MRI scans can help doctors predict which women with endometriosis will benefit from the drug dienogest. Researchers will follow 48 women aged 19-45 who are starting dienogest for the first time. By comparing MRI images before treatment with changes in …
Sponsor: Chungnam National University Sejong Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New ultrasound scalpel may spare ovaries during endometriosis surgery
Knowledge-focused Recruiting nowThis study tests a surgical tool called CUSA Clarity that uses ultrasound to selectively remove endometriosis cyst lining while leaving healthy ovary tissue intact. Researchers will examine cyst wall samples from 10 women to see if the tool can spare ovarian tissue, which may hel…
Sponsor: Kanazawa University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC