Osteonecrosis of the jaw
MONDO:0018378An area of necrotic bone in the mandible or maxilla.
Also known as: ONJ, jaw osteonecrosis, osteonecrosis of jaw
53 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Could your own tooth help regrow jawbone? new trial tests graft and laser combo
Disease control ENROLLING_BY_INVITATIONThis study tests whether a graft made from a person's own extracted tooth, with or without low-level laser therapy, helps regrow jawbone after a tooth is pulled. About 21 healthy adults who need at least two back teeth removed and later replaced with implants will take part. The …
Phase: NA • Sponsor: Istanbul Saglik Bilimleri University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New surgical technique aims to heal jaw bone damage from medications
Disease control ENROLLING_BY_INVITATIONThis study tests a surgical approach for medication-related osteonecrosis of the jaw (MRONJ), a condition where jaw bone dies after certain drugs. Surgeons use a special ultrasonic device (piezosurgery) to remove dead bone, then close the area with a double-layer flap. Twenty pat…
Phase: NA • Sponsor: Tanta University • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Could a common muscle drug and vitamin e heal jaw bone death?
Disease control OngoingThis phase 3 trial tests whether a combination of pentoxifylline (a muscle pain drug) and vitamin E can help heal jaw bone damage caused by osteoporosis or cancer treatments. About 100 people with medication-related jaw bone death will receive either the drug combo plus standard …
Phase: PHASE3 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Gum disease breakthrough? blood concentrate shows promise in small trial
Disease control OngoingThis study tested whether adding injectable Platelet-Rich Fibrin (i-PRF), a natural concentrate from a patient's own blood, to standard deep cleaning improves gum disease outcomes. In 13 adults with moderate to severe periodontitis, one side of the mouth received the combined tre…
Phase: NA • Sponsor: Al-Mustansiriyah University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Weekly Check-Ins could boost patient satisfaction for chronic pain
Knowledge-focused TerminatedThis study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Can a special clinic get workers back on the job faster? norway launches massive study.
Knowledge-focused OngoingThis study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…
Phase: NA • Sponsor: Nordlandssykehuset HF • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Massive PT study mines 4 million records to find what works best
Knowledge-focused OngoingThis study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …
Sponsor: ATI Holdings, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Phone app vs. doctor: can a mobile tool catch infections after surgery?
Knowledge-focused TerminatedThis study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Screw count showdown: does one less screw save jawbone?
Knowledge-focused OngoingThis study looks at whether using 3 screws instead of 4 to attach a full lower-jaw dental bridge affects bone loss around the implants. Fourteen men with no teeth in their lower jaw and no major health issues are being followed with X-rays over time. The goal is to see if fewer s…
Phase: NA • Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC