New surgical technique aims to heal jaw bone damage from medications

NCT ID NCT07177378

ENROLLING_BY_INVITATION Disease control Sponsor: Tanta University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a surgical approach for medication-related osteonecrosis of the jaw (MRONJ), a condition where jaw bone dies after certain drugs. Surgeons use a special ultrasonic device (piezosurgery) to remove dead bone, then close the area with a double-layer flap. Twenty patients are being treated, and researchers will measure pain and wound healing over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: piezosurgery device
What this could lead to: If successful, this surgical technique could offer a better way to treat jaw bone damage caused by certain medications, reducing pain and improving healing.
What could go wrong: This is a very small, early-stage trial with only 20 participants and no control group. Results may not apply to all patients, and the procedure carries standard surgical risks like infection or poor wound healing.

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Conditions

The condition(s) this trial relates to.

osteomyelitis osteonecrosis of the jaw

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOMYELITIS OF JAW

Contacts and locations

Locations

Faculty of Dentistry, Tanta University

Tanta, 3111, Egypt

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