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Can an oxygen gel heal medication-damaged jaw bone better than a blood-derived patch?

NCT ID NCT07725107

Ongoing Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial compares two treatments applied during surgery to help heal jaw bone damage caused by bisphosphonates or similar drugs. One is an oxygen-based gel, the other is a membrane made from the patient's own platelets. Researchers will measure how completely the bone and soft tissue heal, and whether patients have less pain afterward.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an oxygen-based gel (Blue®m) or platelet-rich fibrin (PRF) membrane applied during surgery
What this could lead to
If one of these approaches works better, it could offer a simpler, more effective way to heal jaw bone damage caused by certain medications.
What could go wrong
This is a small, early-stage trial with only 36 participants, so results may not apply to everyone. Both treatments are applied during surgery, and healing may still fail.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Bisphosphonate-Associated Osteonecrosis of the Jaw injury osteonecrosis of the jaw

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BISPHOSPHONATE RELATED OSTEONECROSIS OF THE JAWS (BRONJ) OXYGEN TOPICAL ADMINISTRATION WOUND HEALING

Contacts and locations

Locations

  • Faculty of Dentistry Mansoura University

    Al Mansurah, Egypt

More trials for these conditions

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