Osteoarthritis, spine
MONDO:0006630A degenerative joint disease involving the spine. It is characterized by progressive deterioration of the spinal articular cartilage (cartilage, articular), usually with hardening of the subchondral bone and outgrowth of bone spurs (osteophyte).
88 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Molecular map may guide treatment for mysterious inflammatory illnesses
Disease control CompletedThis study tested whether analyzing a patient's DNA and RNA could help doctors pick the right drug for inflammatory diseases that don't fit standard categories. 32 adults with at least two affected organs (including skin) received one of six targeted therapies based on their mole…
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Hip resurfacing device shows promise in arthritis patients
Disease control CompletedThis study looked at the long-term safety and effectiveness of the Birmingham Hip Resurfacing System, a metal hip implant, in 329 adults with arthritis. The main goal was to see how many patients needed a revision (replacement or removal) within 10 years. The study also measured …
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Knee implant study shows good function after two years
Disease control CompletedThis study looked at how well a specific knee replacement (balanSys UNI) works over time. 116 people with knee arthritis got the implant and were followed for at least 2 years. Doctors measured knee function using the Knee Society Score and checked X-rays for any problems.
Sponsor: Mathys Ltd Bettlach • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New rapid test for infection and inflammation put to the test
Diagnosis CompletedThis study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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New scale could help predict fall risk for hospital patients in turkey
Diagnosis CompletedThis study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…
Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:08 UTC
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New PET tracer aims to light up hidden infections
Diagnosis CompletedThis early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Could a sugar water shot beat steroids for back pain?
Symptom relief CompletedThis study tested whether injecting a sugar solution (dextrose) into the small joints of the lower back can reduce pain and improve function in people with chronic low back pain. Sixty adults aged 40-70 with facet joint arthritis were randomly assigned to receive dextrose, steroi…
Phase: NA • Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Stretching your way to better hips? pilot study tests the idea
Symptom relief CompletedThis pilot study looked at whether passive static stretching can increase hip flexibility in three groups: people who had hip replacement, those with long-term hip pain, and healthy volunteers. Twelve participants followed a 4-week stretching program three times a week under supe…
Sponsor: Omicron beta research • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Simple exercises boost balance in seniors with arthritis
Symptom relief CompletedThis study looked at whether five simple physiotherapy exercises could help improve balance and reaction speed in older adults (ages 65-95) with arthritis of the spine. Sixty participants were split into two groups: one did a three-week exercise program, the other did not. The re…
Phase: NA • Sponsor: Anna Olczak • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Physiotherapy students test muscle relief techniques on themselves
Symptom relief CompletedThis study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…
Phase: NA • Sponsor: Charles University, Czech Republic • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Blood plasma injections show promise for back pain relief
Symptom relief CompletedThis study tested a procedure called 'PRP Spinoplasty' for people with long-term lower back pain from disc disease, facet joint arthritis, and muscle spasms. 35 adults who had not improved with standard care received injections of platelet-rich plasma (PRP) into multiple areas of…
Phase: PHASE2 • Sponsor: Allmed Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Who should control your sedation during surgery? new study compares options
Symptom relief CompletedThis study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Robot-Assisted knee surgery may outperform traditional methods
Symptom relief CompletedThis study compared robotic-assisted total knee replacement to the conventional technique in 95 patients with knee arthritis. The goal was to see if robotic surgery leads to better knee function, less pain, and higher satisfaction two years after the operation. Researchers also c…
Phase: NA • Sponsor: Hospital de Terrassa • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Study explores how family and friends impact caregiver health
Knowledge-focused CompletedThis completed study looked at how the social networks of caregivers affect their stress and health when caring for someone with an inherited disease. Researchers surveyed over 680 participants, including family members and formal caregivers, to understand caregiving burden and s…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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New turkish health survey could improve care for muscle and joint problems
Knowledge-focused CompletedThis study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…
Sponsor: Istanbul Bilgi University • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Scientists analyze genetic markers in stored samples to boost personalized medicine
Knowledge-focused CompletedThis study looked at DNA methylation patterns in stored samples from 90 patients with rare skeletal disorders, sarcomas, or inflammatory arthritis. The goal was to better understand these patterns and explore their potential for diagnosis and treatment. The research aimed to impr…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New device aims to cut spine screw errors in half
Knowledge-focused CompletedThis study tested a new lightweight device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Fourteen adults having spine surgery used the device to guide screw placement. The goal was to see if the device reduces screw misplacement and is safe…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Physios take on ER duty: study tests if they can replace doctors for back pain
Knowledge-focused CompletedThis study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…
Phase: NA • Sponsor: Bern University of Applied Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Hip implant performance under review in completed study
Knowledge-focused CompletedThis study looked back at 54 people who had a hip replacement with a specific part called the CL TRAUMA cemented stem. The goal was to see if the part was safe and worked well. Researchers measured how well patients could move and if they had pain using a standard hip score.
Sponsor: Limacorporate S.p.a • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Hip implant performance tracked in 162 patients
Knowledge-focused CompletedThis study followed 162 people who received a G7 hip cup system during hip replacement surgery. Researchers measured pain, function, and hip movement using standard scores. The goal was to see how the device performs in everyday patients with arthritis or other joint problems.
Sponsor: Zimmer Biomet • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Can CRPS patients imagine movement? new study investigates
Knowledge-focused CompletedThis completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Hip replacement recovery: are old rules unnecessary?
Knowledge-focused CompletedThis study looked at whether hip precautions—like not bending too far or crossing legs—are needed after hip replacement surgery. Over 1,100 patients were randomly assigned to follow precautions or not for six weeks. Researchers tracked dislocations, return to daily activities, an…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Can a simple question curb doctor bias? new study tests individuation in rheumatology
Knowledge-focused CompletedThis completed pilot study tested whether training doctors to ask personalized questions (individuation) could improve care for Black and lower-income patients with rheumatic diseases like lupus and arthritis. Over 200 patients and their rheumatologists took part. The goal was to…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Mind, spirit, and pain: new study explores what chronic pain patients really believe
Knowledge-focused CompletedThis study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Knee implant showdown: which design stays put?
Knowledge-focused CompletedThis study looked at two different designs of knee replacement implants in 60 people with arthritis. The goal was to see how much each implant moved inside the bone over two years using a special X-ray technique called RSA. The findings could help surgeons pick the better implant…
Phase: NA • Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:07 UTC
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Herbal injections for pain: are they safe? large study investigates
Knowledge-focused CompletedThis completed study looked at the safety of pharmacopuncture—herbal extracts injected into acupuncture points—in 1,000 hospitalized adults with spine or joint problems. Researchers tracked infections and other side effects to see how often problems occur. The goal was to gather …
Sponsor: Jaseng Medical Foundation • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:46 UTC