Occlusion precerebral artery

This trial tests whether adding endovascular treatment, a procedure to remove blood clots, to standard medical care improves recovery in people with a mild stroke caused by a blockage in the basilar artery. Participants receive either standard care alone or standard care plus the…

This phase 3 trial tests whether adding tocilizumab, an anti-inflammatory drug, to standard emergency stroke treatment improves outcomes for people with a severe stroke in the back of the brain. About 348 adults will receive either tocilizumab or a placebo by IV right before a pr…

This trial is investigating whether adding a clot-removal procedure, called endovascular treatment, to standard medical care can improve outcomes for people who have had a severe stroke caused by a blockage in the basilar artery, a major vessel at the back of the brain. The study…

This study looks at 518 adults with a severe stroke caused by a blockage in the main artery at the back of the brain. It compares two standard treatments: a procedure to remove the clot (endovascular therapy) versus medication alone. The goal is to see which approach leads to bet…

This study tests a metaverse-based surgical platform that uses extended reality (XR) to help surgeons precisely locate blood vessels during brain bypass surgery. The trial includes 30 adults with moyamoya disease or chronic cerebral ischemia who need an extracranial-intracranial …

This study tests whether adding the antibiotic minocycline to standard stroke treatment can improve recovery in people who had a severe stroke in the back of the brain. After a clot is removed, brain inflammation can limit healing. Minocycline may reduce that inflammation. The tr…

This trial is testing a drug called tenecteplase for people with a severe stroke caused by a blockage in the basilar artery at the back of the brain. About 688 participants will receive either tenecteplase or standard care within 24 hours of symptoms starting, followed by a clot-…

This study compares two ways to reach a blood clot in the basilar artery, a key vessel at the back of the brain, during a stroke. One method uses the femoral artery in the groin, the other uses the radial artery in the wrist. Researchers want to see which approach leads to better…

This study tests whether giving a clot-busting drug (tenecteplase) before transferring patients with a severe stroke in the back of the brain (basilar artery occlusion) to a specialized hospital can improve recovery. About 316 adults who had a stroke 4.5 to 24 hours earlier will …

This study tests whether a procedure to remove a blockage in the neck artery (endovascular treatment) plus standard medical care helps people recover better after a stroke. About 200 adults with acute ischemic stroke from a blocked internal carotid artery will be randomly assigne…

This study tests whether a quick, routine ultrasound measurement (called the resistance index) can accurately identify people with narrowed neck arteries who have normal brain blood flow response. If it works, many patients could avoid a time-consuming, specialized test. The stud…

This study is looking for markers in blood and saliva that can quickly tell if a person is having a stroke, and what kind. Researchers will collect samples from 650 adults with suspected stroke within 24 hours of symptoms. The goal is to develop a fast, accurate test to help emer…

This study looks at whether using sedation instead of general anesthesia helps people having a specific type of stroke (vertebrobasilar) recover better after a procedure to remove a blood clot. About 128 adults with moderate to severe stroke symptoms will be enrolled. The goal is…

This study is building a huge database of up to 800,000 Korean patients with heart or brain vascular disease. By tracking their health over many years, researchers hope to understand the unique patterns and risk factors in this population. The goal is to create a platform that ca…

This study collects blood, clots, and tissue from up to 1000 people having procedures for stroke or other blood vessel problems in the brain. Researchers will analyze these samples to find biological markers and understand inflammation. The goal is to learn more about how stroke …

This study tests a special microscope attachment called GLOW800 that helps surgeons see blood flow and tissues in real time during brain and reconstructive surgery. About 29 adults will take part, and surgeons will rate how well the tool works. The goal is to confirm the device i…

This early study is testing whether a robot can help doctors perform delicate brain blood vessel procedures, such as angiography, embolization, and thrombectomy. Ten patients scheduled for these standard procedures will have them done using a robotic system instead. The main goal…