Common antibiotic could help stroke survivors walk again

NCT ID NCT07594301

First seen May 21, 2026

Summary

This study tests whether the antibiotic minocycline can improve recovery in people who have had a severe stroke in the back of the brain and underwent a procedure to remove a blood clot. About 234 participants will receive either minocycline or a placebo within 24 hours of symptom onset. The goal is to see if minocycline reduces brain inflammation and helps more people regain independence by 90 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Minocycline (an antibiotic)

What this could lead to

If it works, this could point toward a simple, widely available treatment to improve recovery and reduce disability after a severe stroke.

What could go wrong

This is a mid-stage trial with 234 participants, so results are not yet proven. Minocycline may not improve outcomes and could have side effects like dizziness or nausea.

Conditions

The condition(s) this trial relates to.

arterial occlusion Arterial Occlusive Diseases cyclopia sequence ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.