Could a common antibiotic help stroke patients walk again?

NCT ID NCT07594301

Recruiting now Disease control Sponsor: Xiang Luo Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether adding the antibiotic minocycline to standard stroke treatment can improve recovery in people who had a severe stroke in the back of the brain. After a clot is removed, brain inflammation can limit healing. Minocycline may reduce that inflammation. The trial will enroll 234 adults and measure how many regain independence at 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Minocycline (an antibiotic that may also protect brain cells)
What this could lead to: If it works, this could point toward a new add-on treatment to improve recovery and reduce disability after a severe stroke.
What could go wrong: This is an early-to-mid stage trial with 234 participants. Minocycline may not improve outcomes, and there is a risk of side effects like dizziness or nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

arterial occlusion Arterial Occlusive Diseases cyclopia sequence ischemic stroke vertebral artery occlusion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE ARTERIAL OCCLUSION ENDOVASCULAR THROMBECTOMY MINOCYCLINE POSTERIOR CIRCULATION

Contacts and locations

Locations

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430000, China

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