Obsessive-compulsive personality disorder
MONDO:0001158A disorder characterized by an enduring pattern of inflexibility, extreme orderliness, and perfectionism which interfere with efficiency and which may manifest in many different contexts, including work and leisure activities, financial matters, and issues of morality or ethics.
Also known as: OCD, obsessional personality
47 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Drugs and therapy together: a new hope for anxiety, depression, and more?
Disease control CompletedThis early-stage study is testing whether combining standard psychiatric medications (like antidepressants and anti-anxiety drugs) with individual cognitive behavioral therapy can improve symptoms and daily functioning in people with anxiety, depression, PTSD, OCD, bipolar disord…
Phase: PHASE1 • Sponsor: Rakitzi, Stavroula • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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Can talk therapy cut crime risk in people with personality disorders?
Disease control CompletedThis study looked at whether schema therapy, a type of talk therapy, can help people with personality disorders who are in outpatient forensic care. Five participants received therapy for up to two years. Researchers measured changes in their thinking patterns, risk of re-offendi…
Phase: NA • Sponsor: Vrije Universiteit Brussel • Aim: Disease control
Last updated Jun 26, 2026 19:11 UTC
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Computer training shows promise for OCD in small study
Symptom relief CompletedThis study tested whether a computerized training program that targets emotional reactions can help relieve obsessive thoughts and compulsive behaviors in people with OCD. Five adults with OCD completed 14 training sessions over three weeks. The goal was to see if this approach c…
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Aug 15, 2026 00:00 UTC
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Retraining the brain: could a Thought-Focused app ease OCD?
Symptom relief CompletedThis study tests a personalized cognitive training program called CBM-TAF for adults with obsessive-compulsive (OC) symptoms. The program targets a specific thinking pattern known as thought-action fusion (TAF), where people believe having an unwanted thought is as bad as acting …
Phase: NA • Sponsor: Han Joo Lee • Aim: Symptom relief
Last updated Jul 17, 2026 00:00 UTC
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Could a single brain target treat depression, anxiety, and OCD at once?
Symptom relief CompletedThis early-phase trial tests a new brain stimulation target for people with depression plus at least one other psychiatric disorder, such as anxiety, OCD, or PTSD. The treatment uses a non-invasive form of brain stimulation called accelerated intermittent theta burst stimulation …
Phase: EARLY_PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Jul 15, 2026 00:00 UTC
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Caregiver support program shows promise for families facing eating disorders
Symptom relief CompletedThis study tested a program called Family Connections for caregivers of people with both an eating disorder and a personality disorder. The goal was to see if the program could reduce stress and conflict at home. 124 Spanish caregivers took part, and researchers measured things l…
Phase: NA • Sponsor: University of Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Veterans' brain scans could unlock new suicide prevention strategies
Knowledge-focused CompletedThis pilot study uses functional MRI to examine brain activity in trauma-exposed veterans with obsessive-compulsive personality traits, known as overcontrol. Overcontrol can strain relationships and increase suicide risk. The study aims to test whether the brain scanning methods …
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Daydreaming linked to OCD symptoms in new study
Knowledge-focused CompletedThis study looked at how attention and daydreaming influence obsessive thoughts in people with Obsessive Compulsive Disorder (OCD). Researchers compared 80 participants—some with OCD and some without—to see if obsessions change depending on how much the mind wanders. The goal was…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Brain study reveals how OCD affects Decision-Making
Knowledge-focused CompletedThis study looked at how people with obsessive-compulsive disorder (OCD) balance between using habits and goal-directed thinking when making decisions. Researchers used brain scans and mild electrical stimulation to understand the brain circuits involved. The goal was to learn mo…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC