Necrotizing fasciitis
MONDO:0004835Necrotizing fasciitis is a serious infection of the skin, the tissue just beneath the skin (subcutaneous tissue), and the tissue that covers internal organs (fascia). Necrotizing fasciitis can be caused by several different types of bacteria, and the infection can arise suddenly and spread quickly. Early signs include flu-like symptoms and redness and pain around the infection site. A prompt diagnosis and treatment are essential.If the infection is not treated promptly, it can lead to multiple organ failure and death. Treatment typically includes intravenous (IV) antibiotics and surgery to remove infected and dead tissue.
7 clinical trials for this condition and its sub-types.
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Can pressurized oxygen beat Flesh-Eating bacteria?
Disease control Not yet recruitingThis study will test whether adding hyperbaric oxygen therapy to standard care helps people with necrotizing fasciitis, a severe flesh-eating infection. Researchers will compare death rates and complications in 160 adults who receive the treatment versus historical controls. The …
Phase: NA • Sponsor: Corewell Health West • Aim: Disease control
Last updated Jun 26, 2026 16:39 UTC
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Can a simple blood test spot hidden heart trouble during High-Pressure oxygen treatment?
Diagnosis Not yet recruitingThis study looks at whether a blood gas measurement (the difference in carbon dioxide between central venous and arterial blood) can accurately diagnose low cardiac output in patients with septic shock from severe skin infections. About 74 adults will be monitored during hyperbar…
Sponsor: University Hospital, Lille • Aim: Diagnosis
Last updated Jun 27, 2026 12:33 UTC
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Paris network tracks rare Flesh-Eating infections to improve survival
Knowledge-focused Not yet recruitingThis study follows 1,000 patients with rare, life-threatening skin and soft tissue infections who are treated through a special care network in the greater Paris area. Researchers will track survival rates, long-term complications, and quality of life to understand what factors a…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC