Can pressurized oxygen beat Flesh-Eating bacteria?

NCT ID NCT07170020

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study will test whether adding hyperbaric oxygen therapy to standard care helps people with necrotizing fasciitis, a severe flesh-eating infection. Researchers will compare death rates and complications in 160 adults who receive the treatment versus historical controls. The goal is to see if the oxygen treatment improves survival and reduces the need for repeated surgeries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber)

What this could lead to

If it works, this could provide a proven way to lower death and complication rates from severe flesh-eating infections.

What could go wrong

This trial hasn't started yet and is relatively small. Prior evidence is from case studies, so the benefit is uncertain. Hyperbaric oxygen can cause ear or sinus pain and, rarely, lung injury.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

fasciitis necrotizing fasciitis necrotizing soft tissue infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Corewell Health

    Grand Rapids, Michigan, 49503, United States

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••